Biology of Blood and Marrow Transplantation
Volume 13, Issue 11 , Pages 1268-1285, November 2007

Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2007

  • James L.M. Ferrara

      Affiliations

    • University of Michigan, Ann Arbor, Michigan
    • Corresponding Author InformationCorrespondence and reprint requests: James L.M. Ferrara, M.D., 1500 E. Medical Center Dr., 6303 Cancer Center, Ann Arbor, MI.
    • ,
  • Claudio Anasetti

      Affiliations

    • H. Lee Moffitt Cancer Center, Tampa, Florida
    • ,
  • Edward Stadtmauer

      Affiliations

    • University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • Joseph Antin

      Affiliations

    • Dana-Farber Cancer Institute, Boston, Massachusetts
    • ,
  • John Wingard

      Affiliations

    • University of Florida Shands Cancer Center, Gainesville, Florida
    • ,
  • Stephanie Lee

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • John Levine

      Affiliations

    • University of Michigan, Ann Arbor, Michigan
    • ,
  • Kirk Schultz

      Affiliations

    • BC Children’s Hospital/UBC, Vancouver, Canada
    • ,
  • Frederick Appelbaum

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Robert Negrin

      Affiliations

    • Stanford University, Stanford, California
    • ,
  • Sergio Giralt

      Affiliations

    • University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Christopher Bredeson

      Affiliations

    • Medical College of Wisconsin, Milwaukee, Wisconsin
    • ,
  • Helen Heslop

      Affiliations

    • Baylor College of Medicine, Houston, Texas
    • ,
  • Mary Horowitz

      Affiliations

    • CIBMTR, Milwaukee, Wisconsin

Received 17 August 2007; accepted 20 August 2007.

Abstract 

Outcomes of hematopoietic cell transplantation are steadily improving. New techniques have reduced transplant toxicities, and there are new sources of hematopoietic stem cells from unrelated donors. In June 2007 the Blood and Marrow Transplant Clinical Trials Network convened a State of the Science Symposium of more than 200 participants in Ann Arbor to identify the most compelling clinical research opportunities in the field. This report summarizes the symposium’s discussions and identifies eleven high priority clinical trials that the network plans to pursue over the course of the next several years.

Key Words: Hematopoietic cell transplantation, Clinical Trials Network, Clinical trials, Graft versus host disease, Acute myeloid leukemia, Acute lymphocytic leukemia, Chronic lymphocytic leukemia, T cell lymphoma, Hemaphogocytic lymphohistiocytosis, Crohn’s disease, Cell therapy, Biomarkers, Quality of life

 

PII: S1083-8791(07)00384-9

doi:10.1016/j.bbmt.2007.08.005

Biology of Blood and Marrow Transplantation
Volume 13, Issue 11 , Pages 1268-1285, November 2007

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