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Biology of Blood and Marrow Transplantation
Volume 9, Issue 1
, Pages 4-37
, January 2003
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of multiple myeloma: An evidence-based review
References
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Bone marrow transplantation in patients with multiple myeloma: prognostic significance of MR imaging.
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ABO mismatch may affect engraftment in multiple myeloma patients receiving nonmyeloablative conditioning.
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- . Cost-utility analysis of high-dose melphalan with autologous blood stem cell support versus melphalan plus prednisone in patients younger than 60 years with multiple myeloma. Eur J Haematol. 2001;66:328–336
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- . Comparative survival, quality of life and cost-effectiveness of intensive therapy with autologous blood cell transplantation or conventional chemotherapy in multiple myeloma. Bone Marrow Transplant. 1995;16:19–25
- . An economic evaluation of peripheral blood stem cell transplantation as an alternative to autologous bone marrow transplantation in multiple myeloma. Bone Marrow Transplant. 1996;18:1175–1178
- Feasibility and cost-effectiveness of outpatient autotransplants in multiple myeloma. Bone Marrow Transplant. 1997;20:445–450
- . Costs of intensive treatment and follow-up of patients with multiple myeloma. Anticancer Drugs. 1998;9:889–897
- . Treatments for newly diagnosed multiple myeloma: analysis of survival data and cost-effectiveness evaluation. Oncol Rep. 1998;5:1475–1482
- . Cost-effectiveness of high-dose chemotherapy in first-line treatment of advanced multiple myeloma. Br J Haematol. 2001;113:1015–1019
- Gene scanning of VDJH-amplified segments is a clinically relevant technique to detect contaminating tumor cells in the apheresis products of multiple myeloma patients undergoing autologous peripheral blood stem cell transplantation. Bone Marrow Transplant. 2001;28:665–672
- The detection of contaminating clonal cells in apheresis products is related to response and outcome in multiple myeloma undergoing autologous peripheral blood stem cell transplantation. Leukemia. 2000;14:1493–1499
- Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone. Blood. 2001;98:2791–2799
- Molecular and clinical follow-up after stem cell transplantation for multiple myeloma. Ann Hematol. 2001;80:90–95
- . Clinical utility of immunoglobulin heavy chain gene rearrangement identification for tumour cell detection in multiple myeloma. Br J Haematol. 1998;103:1145–1151
- . Myeloma cell contamination of peripheral blood stem cell grafts in patients with multiple myeloma treated by high-dose therapy. Bone Marrow Transplant. 1994;14:47–50
- Quantitative comparison of multiple myeloma tumor contamination in bone marrow harvest and leukapheresis autografts. Bone Marrow Transplant. 1996;18:103–110
- . Comparison of myeloma cell contamination of bone marrow and peripheral blood stem cell harvests. Br J Haematol. 1996;92:614–619
- First and second apheresis in patients with multiple myeloma: no differences in tumor load and hematopoietic stem cell yield. Bone Marrow Transplant. 1998;21:1109–1115
- Linear reduction of clonal cells in stem cell enriched grafts in transplanted multiple myeloma. Br J Haematol. 1999;104:546–552
- Clinical and molecular follow-up by amplification of the CDR-III IgH region in multiple myeloma patients after autologous transplantation of hematopoietic CD34+ stem cells. Haematologica. 1999;84:397–404
- The impact of attaining a minimal disease state after high-dose melphalan and autologous transplantation for multiple myeloma. Br J Haematol. 2001;112:814–819
- Detection of malignant B cells in peripheral blood stem cell collections after chemotherapy in patients with multiple myeloma. Bone Marrow Transplant. 1995;15:707–711
- . Frequency and kinetics of polyclonal and clonal B cells in the peripheral blood of patients being treated for multiple myeloma. Blood. 2000;96:4357–4359
- . A high frequency of circulating B cells share clonotypic Ig heavy-chain VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single-cell and in situ reverse transcriptase-polymerase chain reaction. Blood. 1998;92:2844–2855
- Molecular remission after allogeneic or autologous transplantation of hematopoietic stem cells for multiple myeloma. J Clin Oncol. 2000;18:2273–2281
- Molecular and clinical remissions in multiple myeloma: role of autologous and allogeneic transplantation of hematopoietic cells. J Clin Oncol. 1999;17:208–215
- High-dose sequential chemoradiotherapy in multiple myeloma: residual tumor cells are detectable in bone marrow and peripheral blood cell harvests and after autografting. Blood. 1995;85:1596–1602
- Molecular monitoring of minimal residual disease in patients in long-term complete remission after allogeneic stem cell transplantation for multiple myeloma. Blood. 2000;96:355–357
- Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group. Blood. 2000;96:63–70
- Real-time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease in multiple myeloma. Biol Blood Marrow Transplant. 2000;6:241–253
- Decrease of bone marrow angiogenesis in myeloma patients achieving a remission after chemotherapy. Eur J Haematol. 2001;66:238–244
- . Bone marrow angiogenesis in patients achieving complete response after stem cell transplantation for multiple myeloma. Leukemia. 1999;13:469–472
- Mature plasma cells as indicator of better prognosis in multiple myeloma. New methodology for the assessment of plasma cell morphology. Leuk Res. 1999;23:1133–1140
- . Detection of monoclonal plasma cells in the peripheral blood stem cell harvests of patients with multiple myeloma. Br J Haematol. 1995;89:640–642
- Methods for estimation of bone marrow plasma cell involvement in myeloma: predictive value for response and survival in patients undergoing autologous stem cell transplantation. Am J Hematol. 2001;68:269–275
- . Biochemical markers of bone turnover following high-dose chemotherapy and autografting in multiple myeloma. Blood. 2000;96:2697–2702
- Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: a tool for comparing the efficacy of different treatment strategies and predicting outcome. Blood. 2002;99:1853–1856
- Flow cytometric DNA quantification in immunophenotyped cells as a sensitive method for determination of aneuploid multiple myeloma cells in peripheral blood stem cell harvests and bone marrow after therapy. Bone Marrow Transplant. 1999;23:895–900
- . Plasma cells in peripheral blood stem cell harvests from patients with multiple myeloma are predominantly polyclonal. Bone Marrow Transplant. 1997;20:205–210
- Evaluation of minimal residual disease by interphase FISH in multiple myeloma: does complete remission exist?. Leukemia. 1999;13:641–644
- Interphase FISH: a rapid method for detecting malignant plasma cells in multiple myeloma patients submitted to autologous transplantation. Bone Marrow Transplant. 1999;23:687–694
- Analysis of circulating tumor cells in patients with multiple myeloma during the course of high-dose therapy with peripheral blood stem cell transplantation. Bone Marrow Transplant. 1999;23:1019–1027
- High-sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma. Br J Haematol. 1999;107:121–131
-
Combining an allogeneic graft-versus-myeloma effect with high-dose autologous stem cell rescue in the treatment of multiple myeloma.
[abstract]
Blood. 2001;98:434a
-
Double autologous transplantation improves survival of multiple myeloma patients: final analysis of a prospective randomized study of the Intergroupe Francophone du Myelome (IFM 94).
[abstr]
Blood. 2002;100:5a
-
Myeloablative treatment following intensified chemotherapy in untreated multiple myeloma: a prospective, randomized phase III study.
[abstract]
Blood. 2001;98:815a
-
High-dose therapy autotransplantation/intensification versus continued conventional chemotherapy in multiple myeloma patients responding to initial treatment chemotherapy. Results of a prospective randomized trial from the Spanish Cooperative Group PETHEMA.
[abstract]
Blood. 2001;98:815a
-
.
Randomized trial comparing an intensified therapy (HD-IMC) with a standard high-dose therapy (HD-M) for multiple myeloma.
[abstract]
Blood. 2000;96:797a
☆ Correspondence and reprint requests: Theresa Hahn, PhD, Roswell Park Cancer Institute, Department of Medicine, Elm & Carlton Sts, Buffalo, NY 14263 (e-mail: Theresa.Hahn@RoswellPark.org).
PII: S1083-8791(02)00005-8
doi: 10.1053/bbmt.2003.50002
© 2003 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.
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Biology of Blood and Marrow Transplantation
Volume 9, Issue 1
, Pages 4-37
, January 2003
