Biology of Blood and Marrow Transplantation
Volume 12, Issue 1 , Pages 61-67 , January 2006

High Disease Burden Is Associated with Poor Outcomes for Patients with Acute Myeloid Leukemia Not in Remission Who Undergo Unrelated Donor Cell Transplantation

  • William Blum

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • Corresponding Author InformationCorrespondence and reprint requests: William Blum, MD, Division of Hematology and Oncology and Comprehensive Cancer Center, The Ohio State University, B310 Starling-Loving Hall, 320 W. 10th Ave., Columbus, OH 43210.
    • ,
  • Brian J. Bolwell

      Affiliations

    • Division of Hematology and Oncology, The Cleveland Clinic, Cleveland, Ohio
    • ,
  • Gary Phillips

      Affiliations

    • Department of Biostatistics, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Sherif S. Farag

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Thomas S. Lin

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Belinda R. Avalos

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Sam L. Penza

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Guido Marcucci

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • John C. Byrd

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Matt E. Kalaycio

      Affiliations

    • Division of Hematology and Oncology, The Cleveland Clinic, Cleveland, Ohio
    • ,
  • Ronald M. Sobecks

      Affiliations

    • Division of Hematology and Oncology, The Cleveland Clinic, Cleveland, Ohio
    • ,
  • Brad Pohlman

      Affiliations

    • Division of Hematology and Oncology, The Cleveland Clinic, Cleveland, Ohio
    • ,
  • Stacey Brown

      Affiliations

    • Division of Hematology and Oncology, The Cleveland Clinic, Cleveland, Ohio
    • ,
  • Patrick J. Elder

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio
    • ,
  • Edward A. Copelan

      Affiliations

    • Division of Hematology and Oncology, The Ohio State University Hospitals, Columbus, Ohio

Received 12 January 2005 ,Accepted 27 June 2005.

  • Image Result

    Overall survival was dichotomized in 4 different ways. A, Dichotomization is based on a cutoff of circulating blasts <5000/μL. B, Dichotomization is based on <20% bone marrow blasts. C, Dichotomizatio

    Overall survival was dichotomized in 4 different ways. A, Dichotomization is based on a cutoff of circulating blasts <5000/μL. B, Dichotomization is based on <20% bone marrow blasts. C, Dichotomization is based on whether the subject had any circulating blasts. D, Dichotomization is based on whether the patient had ≤2 prior treatments. All 4 Kaplan-Meier survival curves were tested for equality by using a log-rank test. The P values are shown on each graph.

PII: S1083-8791(05)00424-6

doi: 10.1016/j.bbmt.2005.06.004

Biology of Blood and Marrow Transplantation
Volume 12, Issue 1 , Pages 61-67 , January 2006

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