Biology of Blood and Marrow Transplantation
Volume 12, Issue 2 , Pages 172-183 , February 2006

Nonmyeloablative Stem Cell Transplantation Is an Effective Therapy for Refractory or Relapsed Hodgkin Lymphoma: Results of a Spanish Prospective Cooperative Protocol

  • Iván Alvarez

      Affiliations

    • Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
  • ,
  • Anna Sureda

      Affiliations

    • Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    • Corresponding Author InformationCorrespondence and reprint requests: Anna Sureda, MD, Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, Antoni Maria I Claret, 167, 08025 Barcelona, Spain
  • ,
  • Maria D. Caballero

      Affiliations

    • Hospital Clínico, Salamanca, Spain
  • ,
  • Alvaro Urbano-Ispizua

      Affiliations

    • Hospital Clínic i Provincial, Barcelona, Spain
  • ,
  • Josep M. Ribera

      Affiliations

    • Hospital Germans Trias i Pujol, Barcelona, Spain
  • ,
  • Miguel Canales

      Affiliations

    • Hospital La Paz, Madrid, Spain
  • ,
  • Javier García-Conde

      Affiliations

    • Hospital Clínico y Provincial, Valencia, Spain
  • ,
  • Guillermo Sanz

      Affiliations

    • Hospital La Fe, Valencia, Spain
  • ,
  • Reyes Arranz

      Affiliations

    • Hospital La Princesa, Madrid, Spain
  • ,
  • Maria T. Bernal

      Affiliations

    • Hospital General de Oviedo, Oviedo, Spain
  • ,
  • Javier de la Serna

      Affiliations

    • Hospital Doce de Octubre, Madrid, Spain
  • ,
  • José L. Díez

      Affiliations

    • Hospital Gregorio Marañón, Madrid, Spain
  • ,
  • José M. Moraleda

      Affiliations

    • Hospital Morales Messeguer, Murcia, Spain
  • ,
  • Daniel Rubió-Félix

      Affiliations

    • Hospital Miguel Servet, Zaragoza, Spain
  • ,
  • Blanca Xicoy

      Affiliations

    • Hospital Germans Trias i Pujol, Barcelona, Spain
  • ,
  • Carmen Martínez

      Affiliations

    • Hospital Clínic i Provincial, Barcelona, Spain
  • ,
  • Marivi V. Mateos

      Affiliations

    • Hospital Clínico, Salamanca, Spain
  • ,
  • Jorge Sierra

      Affiliations

    • Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

Received 11 May 2005 ,Accepted 20 September 2005.

  • Image Result

    Cumulative incidence of 100-day and 1-year transplant-related mortality.

    Cumulative incidence of 100-day and 1-year transplant-related mortality.

  • Image Result

    Relationship between progression-free survival (PFS) and patients developing extensive chronic graft-versus-host disease (cGVHD) after transplantation.

    Relationship between progression-free survival (PFS) and patients developing extensive chronic graft-versus-host disease (cGVHD) after transplantation.

  • Image Result

    Actuarial 2-year overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) of the entire series.

    Actuarial 2-year overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) of the entire series.

  • Image Result

    Differences in overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) between chemosensitive (n = 20) and chemorefractory (n = 20) patients.

    Differences in overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) between chemosensitive (n = 20) and chemorefractory (n = 20) patients.

  • Image Result

    Allo-RIC in patients who had a previously failed ASCT. Differences in overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) are shown between late (n = 10)

    Allo-RIC in patients who had a previously failed ASCT. Differences in overall survival (OS) (A), event-free survival (EFS) (B), and progression-free survival (PFS) (C) are shown between late (n = 10) and early (n = 19) relapses.

PII: S1083-8791(05)00673-7

doi: 10.1016/j.bbmt.2005.09.009

Biology of Blood and Marrow Transplantation
Volume 12, Issue 2 , Pages 172-183 , February 2006