Biology of Blood and Marrow Transplantation
Volume 12, Issue 2 , Pages 204-216 , February 2006

Pretransplantation Consolidation Chemotherapy Decreases Leukemia Relapse after Autologous Blood and Bone Marrow Transplants for Acute Myelogenous Leukemia in First Remission

  • Martin S. Tallman

      Affiliations

    • Northwestern University Medical School, Chicago, Illinois
  • ,
  • Waleska S. Pérez

      Affiliations

    • Autologous Blood and Marrow Transplant Registry (ABMTR) Health Policy Institute, Medical College of Wisconsin, Milwaukee, Wisconsin
  • ,
  • Hillard M. Lazarus

      Affiliations

    • University Hospitals of Cleveland, Ireland Cancer Center, Cleveland, Ohio
  • ,
  • Robert Peter Gale

      Affiliations

    • Center for Advanced Studies in Leukemia, Los Angeles, California
  • ,
  • Richard T. Maziarz

      Affiliations

    • Oregon Health and Science University, Portland, Oregon
  • ,
  • Jacob M. Rowe

      Affiliations

    • Rambam Medical Center and Technion, Haifa, Israel
  • ,
  • David I. Marks

      Affiliations

    • Bristol Children’s Hospital, Bristol, U.K
  • ,
  • Jean-Yves Cahn

      Affiliations

    • Hopital Jean Minijoz, Besancon Cedex, France
  • ,
  • Asad Bashey

      Affiliations

    • University of California, San Diego, La Jolla, California
  • ,
  • Michael R. Bishop

      Affiliations

    • National Cancer Institute, Bethesda, Maryland
  • ,
  • Neal Christiansen

      Affiliations

    • University of South Carolina, Columbia, South Carolina
  • ,
  • Stanley R. Frankel

      Affiliations

    • Merck Research Labs, Blue Bell, Pennsylvania
  • ,
  • Juan J. García

      Affiliations

    • Hospital Privado de Cordoba, Cordoba, Peia, Argentina
  • ,
  • Osman Ilhan

      Affiliations

    • Ibini Sinai Hospital, Ankara, Turkey
  • ,
  • Mary J. Laughlin

      Affiliations

    • University Hospitals of Cleveland, Ireland Cancer Center, Cleveland, Ohio
  • ,
  • Jane Liesveld

      Affiliations

    • University of Rochester Medical Center, Rochester, New York
  • ,
  • Charles Linker

      Affiliations

    • University of California San Francisco Medical Center, San Francisco, California
  • ,
  • Mark R. Litzow

      Affiliations

    • Mayo Clinic and Foundation, Rochester, Minnesota
  • ,
  • Selina Luger

      Affiliations

    • University of Pennsylvania Hospital, Philadelphia, Pennsylvania
  • ,
  • Philip L. McCarthy

      Affiliations

    • Roswell Park Cancer Institute, Buffalo, New York
  • ,
  • Gustavo A. Milone

      Affiliations

    • Angélica Ocampo-Hospital and Research Center-Fundaleu, Buenos Aires, Argentina
  • ,
  • Santiago Pavlovsky

      Affiliations

    • Angélica Ocampo-Hospital and Research Center-Fundaleu, Buenos Aires, Argentina
  • ,
  • Gordon L. Phillips

      Affiliations

    • Greenbaum Cancer Center, Baltimore, Maryland
  • ,
  • James A. Russell

      Affiliations

    • Tom Baker Cancer Institute, Calgary, Alberta, Canada
  • ,
  • Ruben A. Saez

      Affiliations

    • Watson Clinic, LLP, Lakeland, Florida
  • ,
  • Gary Schiller

      Affiliations

    • University of California Los Angeles Center for Health Sciences, Los Angeles, California
  • ,
  • Jorge Sierra

      Affiliations

    • Hospital Sant Pau, Barcelona, Spain
  • ,
  • Roy S. Weiner

      Affiliations

    • Tulane University Medical Center, New Orleans, Louisiana
  • ,
  • Axel R. Zander

      Affiliations

    • Universitats-Krankenhaus Eppendorg, Hamburg, Germany; University of Toronto, Toronto, Canada
  • ,
  • Mei-Jie Zhang

      Affiliations

    • Autologous Blood and Marrow Transplant Registry (ABMTR) Health Policy Institute, Medical College of Wisconsin, Milwaukee, Wisconsin
  • ,
  • Armand Keating

      Affiliations

    • University of Minnesota, Minneapolis, Minnesota
  • ,
  • Daniel J. Weisdorf

      Affiliations

    • University of Minnesota, Minneapolis, Minnesota
  • ,
  • Mary M. Horowitz

      Affiliations

    • Autologous Blood and Marrow Transplant Registry (ABMTR) Health Policy Institute, Medical College of Wisconsin, Milwaukee, Wisconsin
    • Corresponding Author InformationCorrespondence and reprint requests: Mary M. Horowitz, MD, MS, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, 8701 Watertown Plank Road, P.O. Box 26509, Milwaukee, WI 53226

Received 1 April 2005 ,Accepted 3 October 2005.

  • Image Result

    Cumulative incidences of TRM (A) and relapse (B) after autologous bone marrow (BM) or PBSC transplantation for AML in first CR by pretransplantation cytarabine consolidation therapy.

    Cumulative incidences of TRM (A) and relapse (B) after autologous bone marrow (BM) or PBSC transplantation for AML in first CR by pretransplantation cytarabine consolidation therapy.

  • Image Result

    Adjusted probabilities of LFS (A) and overall survival (B) after autologous bone marrow (BM) or PBSC transplantation for AML in first CR by cytarabine pretransplantation consolidation therapy.

    Adjusted probabilities of LFS (A) and overall survival (B) after autologous bone marrow (BM) or PBSC transplantation for AML in first CR by cytarabine pretransplantation consolidation therapy.

PII: S1083-8791(05)00683-X

doi: 10.1016/j.bbmt.2005.10.013

Biology of Blood and Marrow Transplantation
Volume 12, Issue 2 , Pages 204-216 , February 2006