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Biology of Blood and Marrow Transplantation
Volume 12, Issue 4
, Pages 397-407
, April 2006
Graft-versus-Leukemia and Graft-versus-Host Reactions after Donor Lymphocyte Infusion Are Initiated by Host-Type Antigen-Presenting Cells and Regulated by Regulatory T Cells in Early and Long-Term Chimeras
References
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- . Donor natural killer (NK1.1+) cells do not play a role in the suppression of GVHD or in the mediation of GVL reactions after DLI . Biol Blood Marrow Transplant . 2001;7:589–595
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- CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation . Nat Med . 2003;9:1144–1150
- Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia . J Clin Invest . 2003;112:1688–1696
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- Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen . Biol Blood Marrow Transplant . 1999;5:133–143
- T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect . Bone Marrow Transplant . 1998;21:543–551
- Donor leukocyte infusions for recurrent hematologic malignancies after allogeneic bone marrow transplantation (impact of infused and residual donor T cells) . Bone Marrow Transplant . 1998;22:1057–1063
- The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation . Blood . 2002;100:3108–3114
PII: S1083-8791(05)01360-1
doi: 10.1016/j.bbmt.2005.11.519
© 2006 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.
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Biology of Blood and Marrow Transplantation
Volume 12, Issue 4
, Pages 397-407
, April 2006
