Biology of Blood and Marrow Transplantation
Volume 13, Issue 1 , Pages 90-99 , January 2007

Allogeneic Bone Marrow Transplantation from Unrelated Human T-Cell Leukemia Virus-I–negative Donors for Adult T-Cell Leukemia/Lymphoma: Retrospective Analysis of Data from the Japan Marrow Donor Program

  • Koji Kato

      Affiliations

    • Department of Hematology, Hamanomachi General Hospital, Fukuoka, Japan
    • Adult Blood and Marrow Transplantation program, University of Michigan Comprehensive Cancer Center, Michigan
    • Corresponding Author InformationCorrespondence and reprint requests: Koji Kato, MD, PhD, Adult Blood and Marrow Transplantation Program, University of Michigan Comprehensive Cancer Center 5303 CCGC 1500E. Medical Center Drive, Ann Arbor, MI 48109-0914.
  • ,
  • Yoshinobu Kanda

      Affiliations

    • Department of Cell Therapy and Transplantation Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Tetsuya Eto

      Affiliations

    • Department of Hematology, Hamanomachi General Hospital, Fukuoka, Japan
  • ,
  • Tsuyoshi Muta

      Affiliations

    • Department of Hematology, Hamanomachi General Hospital, Fukuoka, Japan
  • ,
  • Hisashi Gondo

      Affiliations

    • Department of Hematology, Hamanomachi General Hospital, Fukuoka, Japan
  • ,
  • Shuichi Taniguchi

      Affiliations

    • Department of Hematology, Toranomon General Hospital, Tokyo, Japan
  • ,
  • Tsunefumi Shibuya

      Affiliations

    • Department of Hematology, Hamanomachi General Hospital, Fukuoka, Japan
  • ,
  • Atae Utsunomiya

      Affiliations

    • Department of Hematology, Imamura Bun-in Hospital, Kagoshima, Japan
  • ,
  • Takakazu Kawase

      Affiliations

    • Division of Immunology, Aichi Cancer Center Research Institute, Aichi, Japan
  • ,
  • Shunichi Kato

      Affiliations

    • Department of Cell Transplantation and Regenerative Medicine, Tokai University School of Medicine, Kanagawa, Japan
  • ,
  • Yasuo Morishima

      Affiliations

    • Department of Hematology and Cell Therapy, Aichi Cancer Center Hospital, Aichi, Japan
  • ,
  • Yoshihisa Kodera

      Affiliations

    • Department of Internal Medicine, Japanese Red Cross Nagoya First Hospital, Aichi, Japan
  • ,
  • Mine Harada

      Affiliations

    • Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science, Fukuoka, Japan
  • ,
  • Japan Marrow Donor Program

References 

  1. Uchiyama T, Yodoi J, Sagawa K, et al. Adult T-cell leukemia: clinical and hematologic features of 16 cases. Blood. 1977;50:481–492
  2. Yoshida M, Miyoshi I, Hinuma Y. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci USA. 1982;79:2031–2035
  3. Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T- cell leukaemia-lymphoma (A report from the Lymphoma Study Group (1984-87)). Br J Haematol. 1991;79:428–437
  4. Kuwazuru Y, Hanada S, Furukawa T, et al. Expression of P-glycoprotein in adult T-cell leukemia cells. Blood. 1990;76:2065–2071
  5. Ikeda K, Oka M, Yamada Y, et al. Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes. Int J Cancer. 1999;82:599–604
  6. Taguchi H, Kinoshita KI, Takatsuki K, et al. An intensive chemotherapy of adult T-cell leukemia/lymphoma: CHOP followed by etoposide, vindesine, ranimustine, and mitoxantrone with granulocyte colony-stimulating factor support. J Acquir Immune Defic Syndr Hum Retrovirol. 1996;12:182–186
  7. Yamada Y, Tomonaga M, Fukuda H, et al. A new G-CSF–supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303. Br J Haematol. 2001;113:375–382
  8. Tsukasaki K, Maeda T, Arimura K, et al. Poor outcome of autologous stem cell transplantation for adult T cell leukemia/lymphoma: a case report and review of the literature. Bone Marrow Transplant. 1999;23:87–89
  9. Utsunomiya A, Miyazaki Y, Takatsuka Y, et al. Improved outcome of adult T-cell leukemia/lymphoma with allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2001;27:15–20
  10. Kami M, Hamaki T, Miyakoshi S, et al. Allogeneic haematopoietic stem cell transplantation for the treatment of adult T-cell leukaemia/lymphoma. Br J Haematol. 2003;120:304–309
  11. Fukushima T, Miyazaki Y, Honda S, et al. Allogeneic hematopoietic stem cell transplantation provides sustained long-term survival for patients with adult T-cell leukemia/lymphoma. Leukemia. 2005;19:829–834
  12. Momita S, Ikeda S, Amagasaki T, et al. Survey of anti-human T-cell leukemia virus type I antibody in family members of patients with adult T-cell leukemia. Jpn J Cancer Res. 1990;81:884–889
  13. Chen YC, Wang CH, Su IJ, et al. Infection of human T-cell leukemia virus type I and development of human T-cell leukemia lymphoma in patients with hematologic neoplasms: a possible linkage to blood transfusion. Blood. 1989;74:388–394
  14. Tamaki H, Matsuoka M. Donor-derived T-cell leukemia after bone marrow transplantation. N Engl J Med. 2006;354:1758–1759
  15. Ogata M, Ogata Y, Imamura T, et al. Successful bone marrow transplantation from an unrelated donor in a patient with adult T cell leukemia. Bone Marrow Transplant. 2002;30:699–701
  16. Ishikawa T. Current status of therapeutic approaches to adult T-cell leukemia. Int J Hematol. 2003;78:304–311
  17. Izutsu K, Kanda Y, Ohno H, et al. Unrelated bone marrow transplantation for non-Hodgkin lymphoma: a study from the Japan Marrow Donor Program. Blood. 2004;103:1955–1960
  18. Nakase K, Hara M, Kozuka T, et al. Bone marrow transplantation from unrelated donors for patients with adult T-cell leukaemia/lymphoma. Bone Marrow Transplant. 2006;37:41–44
  19. Terasaki PI, McClelland JD. Microdroplet assay of human serum cytotoxins. Nature. 1964;204:998–1000
  20. Sasazuki T, Juji T, Morishima Y, et al. Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. N Engl J Med. 1998;339:1177–1185
  21. Glucksberg H, Storb R, Fefer A, et al. Clinical manifestation of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors. Transplantation. 1974;18:295–304
  22. Kernan NA, Bartsch G, Ash RC, et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med. 1993;328:593–602
  23. Shulman HM, Sullivan KM, Weiden PL, et al. Chronic cutaneous graft-versus-host syndrome on man: a long-term clinicopathologic study of 20 Seattle patients. Am J Med. 1980;69:204–217
  24. Gooley TA, Leisenring W, Crowley J, et al. Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Stat Med. 1999;18:695–706
  25. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5:649–655
  26. Bierman PJ, Molina L, Nelson G, et al. Matched unrelated donor (MUD) allogeneic bone marrow transplantation for Non-Hodgkin’s lymphoma (NHL): results from the National Marrow Donor Program (NMDP). [abstract] Proc Am Soc Clin Oncol. 1999;18:3a
  27. Morishima Y, Kodera Y, Hirabayashi N, et al. Low incidence of acute GVHD in patients transplanted with marrow from HLA-A, B, DR-compatible unrelated donors among Japanese. Bone Marrow Transplant. 1995;15:235–239
  28. Kodera Y, Morishima Y, Kato S, et al. Analysis of 500 bone marrow transplants from unrelated donors (UR-BMT) facilitated by the Japan Marrow Donor Program: confirmation of UR-BMT as a standard therapy for patients with leukemia and aplastic anemia. Bone Marrow Transplant. 1999;24:995–1003
  29. Harashima N, Kurihara K, Utsunomiya A, et al. Graft-versus-tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation. Cancer Res. 2004;64:391–399
  30. Giralt S, Estey E, Albitar M, et al. Engraftment of allogeneic hematopoietic progenitor ccells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy. Blood. 1997;89:4531–4536
  31. Slavin S, Nagler A, Naparstek E, et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood. 1998;91:756–763
  32. Okamura J, Utsunomiya A, Tanosaki R, et al. Allogeneic stem-cell transplantation with reduced conditioning intensity as a novel immunotherapy and antiviral therapy for adult T-cell leukemia/lymphoma. Blood. 2005;105:4143–4245
  33. Matsushita K, Arima N, Ohtsubo H, et al. Granulocyte-colony stimulating factor-induced proliferation of primary adult T-cell leukaemia cells. Br J Haematol. 1997;96:715–723
  34. Imirizaldu JJ, Esteban JC, Axpe IR, et al. Post-transplantation HTLV-1 myelopathy in three recipients from a single donor. J Neurol Neurosurg Psychiatry. 2003;74:1080–1084

PII: S1083-8791(06)00607-0

doi: 10.1016/j.bbmt.2006.09.002

Biology of Blood and Marrow Transplantation
Volume 13, Issue 1 , Pages 90-99 , January 2007