Biology of Blood and Marrow Transplantation
Volume 13, Issue 5 , Pages 521-529 , May 2007

The Synthetic Triterpenoid, CDDO, Suppresses Alloreactive T Cell Responses and Reduces Murine Early Acute Graft-versus-Host Disease Mortality

  • Kai Sun

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • Both authors contributed equally to this work.
    • ,
  • Minghui Li

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • Both authors contributed equally to this work.
    • ,
  • Marina Konopleva

      Affiliations

    • Section of Molecular Hematology & Therapy, Department of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Sergej Konoplev

      Affiliations

    • Department of Hematopathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • L. Clifton Stephens

      Affiliations

    • Section of Veterinary Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Steven M. Kornblau

      Affiliations

    • Section of Molecular Hematology & Therapy, Department of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Olga Frolova

      Affiliations

    • Section of Molecular Hematology & Therapy, Department of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Danice E.C. Wilkins

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • ,
  • Weihong Ma

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • ,
  • Lisbeth A. Welniak

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • ,
  • Michael Andreeff

      Affiliations

    • Section of Molecular Hematology & Therapy, Department of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • William J. Murphy

      Affiliations

    • Department of Microbiology and Immunology, University of Nevada, Reno, Nevada
    • Corresponding Author InformationCorrespondence and reprint requests: Dr. William J. Murphy, Professor, Department of Microbiology & Immunology, University of Nevada School of Medicine, Mail Stop 199, Reno, NV 89557.

Received 3 October 2006 ,Accepted 24 December 2006.

References 

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 This work was supported by grants R01 CA102282 and 2P30 CA16672.

PII: S1083-8791(06)01313-9

doi: 10.1016/j.bbmt.2006.12.453

Biology of Blood and Marrow Transplantation
Volume 13, Issue 5 , Pages 521-529 , May 2007

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