Biology of Blood and Marrow Transplantation
Volume 13, Issue 6 , Pages 675-682 , June 2007

Major ABO Blood Group Mismatch Increases the Risk for Graft Failure after Unrelated Donor Hematopoietic Stem Cell Transplantation

  • Mats Remberger

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • Center for Allogeneic Stem Cell Transplantation, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • Corresponding Author InformationCorrespondence and reprint requests: Mats Remberger, PhD, Clinical Immunology, Karolinska University Hospital, SE-141 86 Stockholm, Sweden.
    • ,
  • Emma Watz

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • ,
  • Olle Ringdén

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • Center for Allogeneic Stem Cell Transplantation, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • ,
  • Jonas Mattsson

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • Center for Allogeneic Stem Cell Transplantation, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • ,
  • Agneta Shanwell

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    • ,
  • Agneta Wikman

      Affiliations

    • Department of Clinical Immunology and Transfusion Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Received 5 October 2006 ,Accepted 30 January 2007.

  • Image Result

    Cumulative incidence of graft failure (GF) and death without GF in 224 patients with leukemia who received hematopoietic stem cell transplantation (HSCT) from unrelated donors.

    Cumulative incidence of graft failure (GF) and death without GF in 224 patients with leukemia who received hematopoietic stem cell transplantation (HSCT) from unrelated donors.

  • Image Result

    Cumulative incidence of graft failure (GF) depending on a) ABO compatibility and b) grade of HLA match, in 224 patients with leukemia who received hematopoietic stem cell transplantation (HSCT) from u

    Cumulative incidence of graft failure (GF) depending on a) ABO compatibility and b) grade of HLA match, in 224 patients with leukemia who received hematopoietic stem cell transplantation (HSCT) from unrelated donors.

  • Image Result
    Cumulative incidence of graft failure (GF) depending on number of risk factors (RF) found in the multivariate analysis (ABO major mismatch and HLA allele mismatch) in 224 patients with leukemia who re

    Cumulative incidence of graft failure (GF) depending on number of risk factors (RF) found in the multivariate analysis (ABO major mismatch and HLA allele mismatch) in 224 patients with leukemia who received hematopoietic stem cell transplantation (HSCT) from unrelated donors.

PII: S1083-8791(07)00145-0

doi: 10.1016/j.bbmt.2007.01.084

Biology of Blood and Marrow Transplantation
Volume 13, Issue 6 , Pages 675-682 , June 2007

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