Biology of Blood and Marrow Transplantation
Volume 13, Issue 7 , Pages 749-759 , July 2007

Bronchiolitis Obliterans Syndrome (BOS), Bronchiolitis Obliterans Organizing Pneumonia (BOOP), and Other Late-Onset Noninfectious Pulmonary Complications following Allogeneic Hematopoietic Stem Cell Transplantation

  • Satoshi Yoshihara

      Affiliations

    • Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
  • ,
  • Gregory Yanik

      Affiliations

    • Blood and Marrow Transplant Program, University of Michigan, Ann Arbor, Michigan
  • ,
  • Kenneth R. Cooke

      Affiliations

    • Blood and Marrow Transplant Program, University of Michigan, Ann Arbor, Michigan
  • ,
  • Shin Mineishi

      Affiliations

    • Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    • Corresponding Author InformationCorrespondence and reprint requests: Shin Mineishi, MD, Blood and Marrow Transplant Program, University of Michigan, 5303 Cancer Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109.

Received 31 January 2007 ,Accepted 1 May 2007.

  • Image Result

    Schematic diagram of the time of occurrence of IPS, BOOP, and BOS.

    Schematic diagram of the time of occurrence of IPS, BOOP, and BOS.

  • Image Result

    Histology of BO. Characterized by concentric obstruction of the small airways and relative sparing of alveolar space.

    Histology of BO. Characterized by concentric obstruction of the small airways and relative sparing of alveolar space.

  • Image Result

    CT scan of BOS. Mosaic pattern of air trapping is clearly shown in expiratory phase.

    CT scan of BOS. Mosaic pattern of air trapping is clearly shown in expiratory phase.

  • Image Result

    CT scan of BOOP. Consolidation/nodules are shown.

    CT scan of BOOP. Consolidation/nodules are shown.

  • Image Result

    Histology of BOOP. Alveolar space is occupied by organizing pneumonia.

    Histology of BOOP. Alveolar space is occupied by organizing pneumonia.

PII: S1083-8791(07)00274-1

doi: 10.1016/j.bbmt.2007.05.001

Biology of Blood and Marrow Transplantation
Volume 13, Issue 7 , Pages 749-759 , July 2007