High Busulfan Exposure Is Associated with Worse Outcomes in a Daily i.v. Busulfan and Fludarabine Allogeneic Transplant Regimen

Distribution of plasma busulfan AUC values after 3.2 mg/kg once-daily i.v. dosing.

Cumulative incidence of relapse among allogeneic hematopoietic SCT recipients according to busulfan exposure as measured by AUC.

Cumulative incidence of nonrelapse mortality among allogeneic hematopoietic cell transplant recipients according to busulfan exposure as measured by AUC.

OS of allogeneic hematopoietic SCT recipients according to busulfan exposure group as measured by AUC.

PFS of allogeneic hematopoietic SCT recipients according to busulfan exposure as measured by AUC.