Biology of Blood and Marrow Transplantation
Volume 14, Issue 4 , Pages 458-468 , April 2008

Transplantation in Remission Improves the Disease-Free Survival of Patients with Advanced Myelodysplastic Syndromes Treated with Myeloablative T Cell-Depleted Stem Cell Transplants from HLA-Identical Siblings

  • Hugo Castro-Malaspina

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
    • Corresponding Author InformationCorrespondence and reprint requests: Hugo Castro-Malaspina, MD, Bone Marrow Transplantation Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021. Phone: (212) 639-8197. Fax: (212) 717-3371.
  • ,
  • Ann A. Jabubowski

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Esperanza B. Papadopoulos

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Farid Boulad

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • James W. Young

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Nancy A. Kernan

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Miguel A. Perales

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Trudy N. Small

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Katharine Hsu

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Michelle Chiu

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Glenn Heller

      Affiliations

    • Department of Epidemiology and Statistics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Nancy H. Collins

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Suresh C. Jhanwar

      Affiliations

    • Cytogenetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Marcel van den Brink

      Affiliations

    • The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Stephen D. Nimer

      Affiliations

    • Hematology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
  • ,
  • Richard J. O'Reilly

      Affiliations

    • Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY

  • Image Result

    Cumulative incidence of relapse. A, all patients. B, by response to chemotherapy before conditioning.

    Cumulative incidence of relapse. A, all patients. B, by response to chemotherapy before conditioning.

  • Image Result

    Probability of survival. A, Overall survival and disease-free survival (DFS) for all patients. B, DFS by response to chemotherapy before conditioning.

    Probability of survival. A, Overall survival and disease-free survival (DFS) for all patients. B, DFS by response to chemotherapy before conditioning.

  • Image Result

    Cumulative incidence of non-relapse mortality. A, all patients. B, by response to chemotherapy before conditioning.

    Cumulative incidence of non-relapse mortality. A, all patients. B, by response to chemotherapy before conditioning.

PII: S1083-8791(08)00069-4

doi: 10.1016/j.bbmt.2008.02.006

Biology of Blood and Marrow Transplantation
Volume 14, Issue 4 , Pages 458-468 , April 2008