Biology of Blood and Marrow Transplantation
Volume 14, Issue 9, Supplement , Pages 37-44 , September 2008

Advances in the Selection of HLA-Compatible Donors: Refinements in HLA Typing and Matching over the First 20 Years of the National Marrow Donor Program Registry

  • Stephen Spellman

      Affiliations

    • National Marrow Donor Program, Minneapolis, Minnesota
    • Corresponding Author InformationCorrespondence and reprints: Stephen Spellman, National Marrow Donor Program, 3001 Broadway Street NE, Suite 100, Minneapolis, MN 55413.
    • ,
  • Michelle Setterholm

      Affiliations

    • National Marrow Donor Program, Minneapolis, Minnesota
    • ,
  • Martin Maiers

      Affiliations

    • National Marrow Donor Program, Minneapolis, Minnesota
    • ,
  • Harriet Noreen

      Affiliations

    • University of Minnesota Medical Center-Fairview, Minneapolis, Minnesota
    • ,
  • Machteld Oudshoorn

      Affiliations

    • Europdonor, Leiden, The Netherlands
    • ,
  • Marcelo Fernandez-Viña

      Affiliations

    • M.D. Anderson Cancer Center, Houston, Texas
    • ,
  • Effie Petersdorf

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Robert Bray

      Affiliations

    • Emory University, Atlanta, Georgia
    • ,
  • Robert J. Hartzman

      Affiliations

    • C.W. Bill Young/Department of Defense Marrow Donor Naval Medical Research Center, Rockville, Maryland
    • ,
  • Jennifer Ng

      Affiliations

    • C.W. Bill Young/Department of Defense Marrow Donor Naval Medical Research Center, Rockville, Maryland
    • ,
  • Carolyn Katovich Hurley

      Affiliations

    • Georgetown University, Washington, DC

Received 23 April 2008 ,Accepted 1 May 2008.

  • Image Result

    The percent of confirmatory typing results that were in-consistent with the volunteer donor's HLA typing on the NMDP file by year of recruitment. In most cases, the typing in the file was obtained at

    The percent of confirmatory typing results that were in-consistent with the volunteer donor's HLA typing on the NMDP file by year of recruitment. In most cases, the typing in the file was obtained at the time of recruitment. It is not possible to attribute the source of error to the recruitment typing versus other sources of errors.

  • Image Result
    Declining Price of Registry HLA-A, B, DRB1 typing. The change in HLA-A, -B, -DRB1 recruitment typing cost for the NMDP registry over the past 10 years.

    Declining Price of Registry HLA-A, B, DRB1 typing. The change in HLA-A, -B, -DRB1 recruitment typing cost for the NMDP registry over the past 10 years.

 STATEMENT OF CONFLICT OF INTEREST: See Acknowledgements on page 43.

PII: S1083-8791(08)00183-3

doi: 10.1016/j.bbmt.2008.05.001

Biology of Blood and Marrow Transplantation
Volume 14, Issue 9, Supplement , Pages 37-44 , September 2008

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