« Previous Biology of Blood and Marrow Transplantation
Volume 14, Issue 9, Supplement , Pages 45-53 , September 2008

National Marrow Donor Program HLA Matching Guidelines for Unrelated Adult Donor Hematopoietic Cell Transplants

Robert A. Bray
- Department of Pathology, Emory University, Atlanta, Georgia
Carolyn K. Hurley
- Department of Oncology, Georgetown University, Washington, DC
Naynesh R. Kamani
- Division of Blood and Marrow Transplantation/Immunology, Children's National Medical Center, Washington, DC
Ann Woolfrey
- Fred Hutchinson Cancer Research Center, Seattle, Washington
Carlheinz Müller
- German National Bone Marrow Registry/ZKRD, Ulm, Germany
Stephen Spellman
- National Marrow Donor Program, Minneapolis, Minnesota
- Correspondence and reprint requests: Stephen Spellman, National Marrow Donor Program, 3001 Broadway Street NE, Minneapolis, MN 55413.
Michelle Setterholm
- National Marrow Donor Program, Minneapolis, Minnesota
Dennis L. Confer
- National Marrow Donor Program, Minneapolis, Minnesota

Received 20 February 2008 ,Accepted 17 June 2008.

Example of an NMDP search report. The columns labeled “Match Grade/Calculation” include a letter indicating the match status of each allele at the locus indicated (A, allele match; P, potential allele

Example of an NMDP search report. The columns labeled “Match Grade/Calculation” include a letter indicating the match status of each allele at the locus indicated (A, allele match; P, potential allele match), the probability of matching both alleles at the locus (100% for the first donor at each locus), and the probability of a 6/6 HLA-A,-B,-DRB1 allele match (Pr[6] 100% for first donor) and of at most a 5/6 allele match (Pr[5] 0%).
- Full-Size Image
- Download to PowerPoint