Biology of Blood and Marrow Transplantation
Volume 15, Issue 4 , Pages 490-495 , April 2009

Clinical Utility of Computed Tomography Screening of Chest, Abdomen, and Sinuses before Hematopoietic Stem Cell Transplantation: The St. Jude Experience

  • Kimberly A. Kasow

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
    • Corresponding Author InformationCorrespondence and reprint requests: Kimberly A. Kasow, DO, Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 260, Memphis, TN 38105.
  • ,
  • Jennifer Krueger

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Deo Kumar Srivastava

      Affiliations

    • Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Chenghong Li

      Affiliations

    • Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Raymond Barfield

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Wing Leung

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Edwin M. Horwitz

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Renee Madden

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Paul Woodard

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Ishtiaq Hussain

      Affiliations

    • Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • M. Beth McCarville

      Affiliations

    • Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Rupert Handgretinger

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee
  • ,
  • Gregory A. Hale

      Affiliations

    • Division of Bone Marrow Transplantation & Cellular Therapy, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee

Received 30 May 2008 ,Accepted 23 November 2008.

References 

  1. Afessa B, Peters SG. Major complications following hematopoietic stem cell transplantation. Semin Respir Crit Care Med. 2006;27:297–309
  2. Junghanss C, Marr KA, Carter RA, et al. Incident and outcome of bacterial and fungal infections following nonmyeloablative compared with myeloablative allogeneic hematopoietic stem cell transplantation: a matched control study. Biol Blood Marrow Transplant. 2002;8:512–520
  3. Bjorklund A, Aschan J, Labopin M, et al. Risk factors for fatal infectious complications developing late after allogeneic stem cell transplantation. Bone Marrow Transplant. 2007;40:1055–1062
  4. Kanne JP, Godwin JD, Franquet T, et al. Viral pneumonia after hematopoietic stem cell transplantation: high-resolution CT findings. J Thorac Imaging. 2007;23:292–299
  5. Leung W, Ahn H, Rose SR, et al. A prospective cohort study of late sequelae of pediatric allogeneic hematopoietic stem cell transplantation. Medicine. 2007;86:215–224
  6. Uderzo C, Pillon M, Corti P, et al. Impact of cumulative anthracycline dose, preparative regimen and chronic graft-versus-host disease on pulmonary and cardiac function in children 5 years after allogeneic hematopoietic stem cell transplantation: a prospective evaluation on behalf of the EBMT Pediatric Diseases and Late Effects Working Parties. Bone Marrow Transplant. 2007;39:667–675
  7. Shrimpton PC, Wall BF. Reference doses for paediatric computed tomography. Radiat Protect Dosim. 2000;90:249–252
  8. http://www.acr.org/accreditation/computed/qc_forms/Phantom_Testing_InstructionFinal.aspx.
  9. Cameron JR. Are X-rays safe? Available at: http://www.angelfire.com/mo/radioadaptive/jcameron1.html. May 22, 1998.
  10. Brody AS, Frush DP, Huda W, Brent RL. Radiation risk to children from computed tomography. Pediatrics. 2007;120:677–682
  11. Billings KR, Lowe LH, Aquino VM, Biavati MJ. Screening sinus CT in pediatric bone marrow transplant patients. Int J Pediatr Otorhinolaryngol. 2000;52:253–260
  12. Brenner DJ, Hall EJ. Computed tomography-an increasing source of radiation exposure. N Engl J Med. 2007;357:2277–2284

 Financial disclosure: See Acknowledgments on page 495.

PII: S1083-8791(08)00583-1

doi: 10.1016/j.bbmt.2008.11.033

Biology of Blood and Marrow Transplantation
Volume 15, Issue 4 , Pages 490-495 , April 2009