Biology of Blood and Marrow Transplantation
Volume 15, Issue 4 , Pages 505-511 , April 2009

First-Line Therapy for Chronic Graft-versus-Host Disease that Includes Low-Dose Methotrexate Is Associated with a High Response Rate

Received 28 September 2008 ,Accepted 15 December 2008.

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    Cumulative overall response rate after MTX therapy. Seventy-one of 86 patients achieved overall response with a median of 4 (1-10) MTX administrations.

    Cumulative overall response rate after MTX therapy. Seventy-one of 86 patients achieved overall response with a median of 4 (1-10) MTX administrations.

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    Cumulative cGVHD recurrence after MTX discontinued. Among the 71 patients who obtained a response, 25 flared up after a median of 50 days (range: 15-602 days) from the last MTX.

    Cumulative cGVHD recurrence after MTX discontinued. Among the 71 patients who obtained a response, 25 flared up after a median of 50 days (range: 15-602 days) from the last MTX.

 Financial disclosure: See Acknowledgments on page 510.

PII: S1083-8791(08)01103-8

doi: 10.1016/j.bbmt.2008.12.493

Biology of Blood and Marrow Transplantation
Volume 15, Issue 4 , Pages 505-511 , April 2009

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