Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1005-1013 , September 2009

Efficacy of Rituximab in the Setting of Steroid-Refractory Chronic Graft-versus-Host Disease: A Systematic Review and Meta-Analysis

  • Mohamed A. Kharfan-Dabaja

      Affiliations

    • Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, Florida
    • Department of Hematology, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Asmita R. Mhaskar

      Affiliations

    • Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida
    • ,
  • Benjamin Djulbegovic

      Affiliations

    • Department of Hematology, Moffitt Cancer Center, Tampa, Florida
    • Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida
    • Center for Evidence-Based Medicine, University of South Florida, College of Medicine, Tampa, Florida
    • ,
  • Corey Cutler

      Affiliations

    • Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
    • ,
  • Mohamad Mohty

      Affiliations

    • Hematology Clinic, Hospital Center of the University of Nantes, Nantes, France
    • ,
  • Ambuj Kumar

      Affiliations

    • Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida
    • Center for Evidence-Based Medicine, University of South Florida, College of Medicine, Tampa, Florida
    • Corresponding Author InformationCorrespondence and reprint requests: Ambuj Kumar, MD, MPH, Moffitt Cancer Center & Research Institute, College of Medicine, University of South Florida, 12902 Magnolia Drive, MRC 232A, Tampa, FL 33612.

Received 25 February 2009 ,Accepted 6 April 2009.

  • Image Result

    Identification and selection of studies.

    Identification and selection of studies.

  • Image Result

    Forest plot for the outcomes of survival, overall response and organ specific response (skin and liver). The summary effect estimate (proportion) for individual studies are indicated by black rectangl

    Forest plot for the outcomes of survival, overall response and organ specific response (skin and liver). The summary effect estimate (proportion) for individual studies are indicated by black rectangles (the size of the rectangle is proportional to the study weight), with the lines representing 95% confidence intervals (CIs). The overall summary effect estimate (proportion) and 95% CI are indicated by the diamond.

 Financial disclosure: See Acknowledgments on page 1012.

PII: S1083-8791(09)00187-6

doi: 10.1016/j.bbmt.2009.04.003

Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1005-1013 , September 2009

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