Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1077-1085 , September 2009

High-Dose Iodine-131-Metaiodobenzylguanidine with Haploidentical Stem Cell Transplantation and Posttransplant Immunotherapy in Children with Relapsed/Refractory Neuroblastoma

  • Jacek Toporski

      Affiliations

    • Department of Pediatric Oncology, University Hospital, Lund, Sweden
    • Corresponding Author InformationCorrespondence and reprint requests: Jacek Toporski, MD, Department of Pediatric Oncology, University Hospital, SE-221 85 Lund, Sweden.
    • ,
  • Michael Garkavij

      Affiliations

    • Department of Oncology, University Hospital, Lund, Sweden
    • ,
  • Jan Tennvall

      Affiliations

    • Department of Oncology, University Hospital, Lund, Sweden
    • ,
  • Ingrid Øra

      Affiliations

    • Department of Pediatric Oncology, University Hospital, Lund, Sweden
    • ,
  • Katarina Sjögreen Gleisner

      Affiliations

    • Department of Radiation Physics, University Hospital, Lund, Sweden
    • ,
  • Josefina H. Dykes

      Affiliations

    • Blood Center, University Hospital, Lund, Sweden
    • Division of Hematology and Transfusion Medicine, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    • ,
  • Stig Lenhoff

      Affiliations

    • Department of Hematology, University Hospital, Lund, Sweden
    • ,
  • Gunnar Juliusson

      Affiliations

    • Department of Hematology, University Hospital, Lund, Sweden
    • Stem Cell Center, Lund University, Lund, Sweden
    • ,
  • Stefan Scheding

      Affiliations

    • Department of Hematology, University Hospital, Lund, Sweden
    • Stem Cell Center, Lund University, Lund, Sweden
    • ,
  • Dominik Turkiewicz

      Affiliations

    • Department of Pediatric Oncology, University Hospital, Lund, Sweden
    • Department of Pediatric Hematology and Oncology, Medical University, Wrocław, Poland
    • ,
  • Albert N. Békássy

      Affiliations

    • Department of Pediatric Oncology, University Hospital, Lund, Sweden

Received 22 March 2009 ,Accepted 7 May 2009.

  • Image Result

    Posttransplant chimerism analysis, virus reactivation, time of DLIs, and outcomes. Abbreviations: UPN, unique patient number; CMV, cytomegalovirus reactivation; BKV, BK virus reactivation; AdV, adenov

    Posttransplant chimerism analysis, virus reactivation, time of DLIs, and outcomes. Abbreviations: UPN, unique patient number; CMV, cytomegalovirus reactivation; BKV, BK virus reactivation; AdV, adenovirus reactivation; aGVHD, acute graft-versus-host disease; ATG, antithymocyte globulin treatment; DLI, donor lymphocyte infusion; DoD, died of disease; A&W, alive and well; NB, neuroblastoma; BM, bone marrow; m, months after haplo-SCT.

  • Image Result
    Immunological recovery (median values).

    Immunological recovery (median values).

 Financial disclosure: See Acknowledgments on page 1084.

PII: S1083-8791(09)00233-X

doi: 10.1016/j.bbmt.2009.05.007

Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1077-1085 , September 2009

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