Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1122-1129 , September 2009

Low Relapse without Excessive Transplant-Related Mortality following Myeloablative Cord Blood Transplantation for Acute Leukemia in Complete Remission: A Matched Cohort Analysis

  • Jonathan A. Gutman

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • Medicine and Pediatrics, University of Washington, Seattle, Washington
    • Corresponding Author InformationCorrespondence and reprint requests: Jonathan A. Gutman, Fred Hutchinson Cancer Research Center/University of Washington, D2-100, 1100 Fairview Avenue North, Seattle, WA 98109.
    • ,
  • Wendy Leisenring

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Frederick R. Appelbaum

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • Medicine and Pediatrics, University of Washington, Seattle, Washington
    • ,
  • Ann E. Woolfrey

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • Medicine and Pediatrics, University of Washington, Seattle, Washington
    • ,
  • Colleen Delaney

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
    • Medicine and Pediatrics, University of Washington, Seattle, Washington

Received 15 April 2009 ,Accepted 18 May 2009.

  • Image Result

    Cumulative incidence of relapse and TRM by cohort. Relapse (A) and TRM (B).

    Cumulative incidence of relapse and TRM by cohort. Relapse (A) and TRM (B).

  • Image Result

    Cumulative incidence GVHD by cohort. Grade II-IV GVHD through day 100 (A), grade III-IV GVHD through day 100 (B), and composite endpoint of equal to or greater than moderate cGVHD or grade II-IV late,

    Cumulative incidence GVHD by cohort. Grade II-IV GVHD through day 100 (A), grade III-IV GVHD through day 100 (B), and composite endpoint of equal to or greater than moderate cGVHD or grade II-IV late, persistent, or relapsing aGVHD (C).

  • Image Result
    OS and RFS. Kaplan-Meier estimates of OS (A) and RFS (B).

    OS and RFS. Kaplan-Meier estimates of OS (A) and RFS (B).

 Financial disclosure: See Acknowledgments on page 1128.

PII: S1083-8791(09)00252-3

doi: 10.1016/j.bbmt.2009.05.014

Biology of Blood and Marrow Transplantation
Volume 15, Issue 9 , Pages 1122-1129 , September 2009

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