Biology of Blood and Marrow Transplantation
Volume 15, Issue 10 , Pages 1271-1276 , October 2009

Osteochondroma after Hematopoietic Stem Cell Transplantation in Childhood. An Italian Study on Behalf of the AIEOP-HSCT Group

  • Maura Faraci

      Affiliations

    • Department of Hematology-Oncology, Bone Marrow Transplant Unit, G. Gaslini Children's Hospital, Genova, Italy
    • Corresponding Author InformationCorrespondence and reprint requests: Maura Faraci, MD, Department of Oncology/Oncology, Stem Cell Transplantation Section, G. Gaslini Children's Hospital, Largo G. Gaslini, 5; 16147 Genova, Italy.
    • ,
  • Francesca Bagnasco

      Affiliations

    • Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Children's Hospital, Genova, Italy
    • ,
  • Paola Corti

      Affiliations

    • Bone Marrow Unit, Clinic of Pediatrics, University of Milano Bicocca, San Gerardo Hospital, Monza, Italy
    • ,
  • Chiara Messina

      Affiliations

    • Clinic of Pediatric Hematology Oncology, Department of Pediatrics, University of Padova, Padova, Italy
    • ,
  • Franca Fagioli

      Affiliations

    • Clinic of Pediatric Hematology Oncology, Department of Pediatrics, Regina Margherita Pediatric Hospital, Torino, Italy
    • ,
  • Marta Podda

      Affiliations

    • Pediatric Oncology Unit, Foundation IRCSS, Institute National of Tumors, Milano, Italy
    • ,
  • Arcangelo Prete

      Affiliations

    • Department of Pediatrics, University of Bologna, Sant'Orsola Hospital, Bologna, Italy
    • ,
  • Desirè Caselli

      Affiliations

    • DAI, Oncology-Oncology and Home Care, AUO Mayer, Firenze, Italy
    • ,
  • Edoardo Lanino

      Affiliations

    • Department of Hematology-Oncology, Bone Marrow Transplant Unit, G. Gaslini Children's Hospital, Genova, Italy
    • ,
  • Giorgio Dini

      Affiliations

    • Department of Hematology-Oncology, Bone Marrow Transplant Unit, G. Gaslini Children's Hospital, Genova, Italy
    • ,
  • Roberto Rondelli

      Affiliations

    • Department of Pediatrics, University of Bologna, Sant'Orsola Hospital, Bologna, Italy
    • ,
  • Riccardo Haupt

      Affiliations

    • Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Children's Hospital, Genova, Italy
    • ,
  • AIEOP-HSCT Group

Received 6 April 2009 ,Accepted 4 June 2009.

References 

  1. Bovée JV. Multiple osteochondromas. Orphanet J Rare Dis. 2008;13:3
  2. Taitz J, Cohn RJ, White L, Russell SJ, Vowels MR. Osteochondroma after total body irradiation: an age-related complication. Pediatr Blood Cancer. 2004;42:225–229
  3. Bordigoni P, Turello R, Clement L, et al. Osteochondroma after pediatric hematopoietic stem cell transplantation: report of eight cases. Bone Marrow Transplant. 2002;29:611–614
  4. Maeda G, Yokoyama R, Ohtomo K, et al. Osteochondroma after total body irradiation in bone marrow transplant recipients: report of two cases. Jpn J Clin Oncol. 1996;26:480–483
  5. Sanders JE, Guthrie KA, Hoffmeister PA, Woolfrey AE, Carpenter PA, Appelbaum FR. Final adult height of patients who received hematopoietic cell transplantation in childhood. Blood. 2005;105:1348–1354
  6. Marcovici PA, Berdon WE, Liebling MS. Osteochondromas and growth retardation secondary to externally or internally administered radiation in childhood. Pediatr Radiol. 2007;37:301–304
  7. Fletcher BD, Crom DB, Krance RA, Kun LE. Radiation-induced bone abnormalities after bone marrow transplantation for childhood leukemia. Radiology. 1994;191:231–235
  8. Cohen A, Rovelli A, Bakker B, et al. Final height of patients who underwent bone marrow transplantation for hematological disorders during childhood: a study by the Working Party for Late Effects-EBMT. Blood. 1999;93:4109–4115
  9. Mahboubi S, Dormans JP, D'Angio G. Malignant degeneration of radiation-induced osteochondroma. Skeletal Radiol. 1997;26:195–198
  10. Eagleton MD, Seaman WB. Radiation therapy of neuroblastoma. Radiology. 1957;68:1–8
  11. Harper GD, Dicks-Mireaux C, Leiper AD. Total body irradiation-induced osteochondromata. J Pediatr Orthop. 1998;18:356–358

 Financial disclosure: See Acknowledgments on page 1276.

PII: S1083-8791(09)00275-4

doi: 10.1016/j.bbmt.2009.06.003

Biology of Blood and Marrow Transplantation
Volume 15, Issue 10 , Pages 1271-1276 , October 2009

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