Biology of Blood and Marrow Transplantation
Volume 16, Issue 3 , Pages 333-343 , March 2010

An Age-Dependent Pharmacokinetic Study of Intravenous and Oral Mycophenolate Mofetil in Combination with Tacrolimus for GVHD Prophylaxis in Pediatric Allogeneic Stem Cell Transplantation Recipients

  • Monica Bhatia

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Olga Militano

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Zhezhen Jin

      Affiliations

    • Department of Biostatistics, Columbia University, New York, New York
    • ,
  • Michal Figurski

      Affiliations

    • Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
    • ,
  • Leslie Shaw

      Affiliations

    • Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania
    • ,
  • Virginia Moore

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Erin Morris

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Bradford Tallamy

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Carmella van deVen

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Janet Ayello

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • LeeAnn Baxter-Lowe

      Affiliations

    • Department of Surgery, University of California, San Francisco, California
    • ,
  • Prakash Satwani

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Diane George

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • M. Brigid Bradley

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • James Garvin

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • ,
  • Mitchell S. Cairo

      Affiliations

    • Department of Pediatrics, Columbia University, New York, New York
    • Department of Medicine, Columbia University, Morgan Stanley Children's Hospital, NewYork-Presbyterian Hospital, New York, New York
    • Department of Pathology, Columbia University, Morgan Stanley Children's Hospital, NewYork-Presbyterian Hospital, New York, New York
    • Corresponding Author InformationCorrespondence and reprint requests: Mitchell S. Cairo, MD, Division of Pediatric Blood and Marrow Transplantation, Pediatrics, Medicine, Pathology, Columbia University, 3959 Broadway, CHN 10-03, New York, NY 10032.

  • Image Result

    Probability of developing aGVHD or cGVHD. Probability of developing aGVHD grade II-IV (), grade III-IV (), or cGVHD () determined by Kaplan Meier method in patients receiving AlloSCT.

    Probability of developing aGVHD or cGVHD. Probability of developing aGVHD grade II-IV (), grade III-IV (), or cGVHD () determined by Kaplan Meier method in patients receiving AlloSCT.

  • Image Result

    Probability of OS. Probability of OS determined by Kaplan Meier method in all patients following AlloSCT.

    Probability of OS. Probability of OS determined by Kaplan Meier method in all patients following AlloSCT.

 Financial disclosure: See Acknowledgments on page 341.

 The first 2 authors should be considered equal coprimary first authors.

PII: S1083-8791(09)00463-7

doi: 10.1016/j.bbmt.2009.10.007

Biology of Blood and Marrow Transplantation
Volume 16, Issue 3 , Pages 333-343 , March 2010

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