Biology of Blood and Marrow Transplantation
Volume 16, Issue 1, Supplement , Pages S57-S63 , January 2010

HLA-Haploidentical Stem Cell Transplantation for Hematologic Malignancies

  • Ephraim J. Fuchs

      Affiliations

    • Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland
    • Corresponding Author InformationCorrespondence and reprint requests: Ephraim J. Fuchs, M.D., M.B.A., Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 488 Cancer Research Building, 1650 Orleans Street, Baltimore, MD 21231.
    • ,
  • Xiao-jun Huang

      Affiliations

    • Institute of Hematology, People's Hospital, Peking University, Beijing, People's Republic of China
    • ,
  • Jeffrey S. Miller

      Affiliations

    • Division of Hematology, Oncology and Transplantation, University of Minnesota Cancer Center, Minneapolis, Minnesota

Received 15 September 2009 ,Accepted 29 October 2009.

  • Image Result

    Treatment schema for nonmyeloablative conditioning and HLA-haploidentical bone marrow transplantation. From ref. 11.

    Treatment schema for nonmyeloablative conditioning and HLA-haploidentical bone marrow transplantation. From ref. 11.

  • Image Result

    Effect of HLA-DRB1 antigen mismatch (a,c) or HLA Class I allele mismatches (b,d) in the GVH direction on relapse, NRM (a,b), and EFS (c,d) after nonmyeloablative, HLA-haploidentical bone marrow transp

    Effect of HLA-DRB1 antigen mismatch (a,c) or HLA Class I allele mismatches (b,d) in the GVH direction on relapse, NRM (a,b), and EFS (c,d) after nonmyeloablative, HLA-haploidentical bone marrow transplantation with high-dose, posttransplantation cyclophosphamide.

  • Image Result
    The myeloablative conditioning regimen for HLA-haploidentical HSCT at Peking University. Ara-C: cytosine arabinoside; Bu: busulfan; Cy: cyclophosphamide; MeCCNU: simustine; ATG: antithymocyte globulin

    The myeloablative conditioning regimen for HLA-haploidentical HSCT at Peking University. Ara-C: cytosine arabinoside; Bu: busulfan; Cy: cyclophosphamide; MeCCNU: simustine; ATG: antithymocyte globulin.

 Financial disclosure: See Acknowledgments on page 62.

PII: S1083-8791(09)00514-X

doi: 10.1016/j.bbmt.2009.10.032

Biology of Blood and Marrow Transplantation
Volume 16, Issue 1, Supplement , Pages S57-S63 , January 2010

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