« Previous
Next »
Biology of Blood and Marrow Transplantation
Volume 16, Issue 3
, Pages 311-319
, March 2010
Chemokine Receptor CCR5 Mediates AlloImmune Responses in Graft-versus-Host Disease
References
- . Haematopoietic cell transplantation as immunotherapy. Nature. 2001;411:385–389
- . The Pathology of Organ Transplantation. London: Butterworth Publishers, Inc.; 1990;229-260
- . The pathophysiology of graft-versus-host disease. In: Thomas ED, Blume KG, Forman SJ editor. Hematopoietic Cell Transplantation. Boston, MA: Blackwell Scientific Publications; 1994;p. 305–315
- . Does graft-versus-host disease attack epithelial stem cells?. Mol Med Today. 1996;2:114–119
- . Graft-versus-host disease as a Th1-type process: regulation by donor cells of Th2 cytokine phenotype. In: Ferrara JLM, Deeg HJ, Burakoff SJ editor. Graft-vs.-Host Disease. New York: Marcel Dekker Inc.; 1997;p. 479–500
- . Pathogenesis of acute graft-versus-host disease: cytokines and cellular effectors. J Hematother Stem Cell Res. 2000;9:299–306
- . Chemokines as regulators of T cell differentiation. Nat Immunol. 2001;2:102–107
- . Lymphocyte traffic control by chemokines. Nat Immunol. 2001;2:123–128
- . Chemokines and the tissue-specific migration of lymphocytes. Immunity. 2002;16:1–4
- . The role of chemokines in human immunodeficiency virus infection. Immunol Rev. 2000;177:79–87
- . Differentiation of human CD8+ T cells from a memory to memory/effector phenotype. J Immunol. 2002;168:5538–5550
- . Functional expression of the chemokine receptor CCR5 on virus epitope-specific memory and effector CD8+ T cells. J Immunol. 2002;168:2225–2232
- Related active participation of CCR5+CD8+ T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease. J Clin Invest. 1999;104:49–57
- . Murine T lymphocytes incapable of producing macrophage inhibitory protein-1 are impaired in causing graft-versus-host disease across a class I but not class II major histocompatibility complex barrier. Blood. 1999;93:43–50
- T-lymphocyte production of macrophage inflammatory protein-1alpha is critical to the recruitment of CD8+ T cells to the liver, lung, and spleen during graft-versus-host disease. Blood. 2000;96:2973–2980
- Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction. Nat Immunol. 2003;4:154–160
- Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning. J Immunol. 2004;173:845–854
- . Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1 alpha (CCL3) after allogeneic BMT in mice. Blood. 2003;101:3714–3721
- Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med. 2004;5:510–517
- . The role of B Cells in the pathogenesis of graft-versus-host disease. Blood. 2009;2009 Sep 11 [Epub ahead of print]
- . Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis. J Allergy Clin Immunol. 2009;124:753–760
- Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: differential activation states suggest distinct functions. J Leukoc Biol. 2008;84:143–151
- Expression of chemokines and chemokine receptors during human renal transplant rejection. Am J Kidney Dis. 2001;37:518–531
- CC chemokine receptor 5 and renal-transplant survival. Lancet. 2001;357:1758–1761
- . CCR5 expression on cells from HLA-matched unrelated marrow donors and graft-versus-host disease. Biol Blood Marrow Transplant. 2009;doi: 10.1016/j.bbmt.2009.05.003
- Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med. 1998;338:962–968
- AML-loaded DC generate Th1-type cellular immune responses in vitro. Cytotherapy. 2006;8:95–104
- Functional assessment and specific depletion of alloreactive human T cells using flow cytometry. Blood. 2004;104:3429–3436
- . Chemokines: a new classification system and their role in immunity. Immunity. 2000;12:121–127
- . Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med. 1998;187:875–883
- . T cell effector subsets: extending the Th1/Th2 paradigm. Adv Immunol. 2001;78:233–266
- . Increased gene expression of chemokine receptors is correlated with acute graft-versus-host disease after allogeneic stem cell transplantation. Biol Blood Marrow Transplant. 2005;11:280–287
- . Gene-expression profiles of peripheral blood mononuclear cell subpopulations in acute graft-vs-host disease following cord blood transplantation. Exp Hematol. 2008;36:1760–1770
- . CCR5 deletion mutation and its association with the risk of developing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Haematologica. 2006;91:1628–1634
- . Chemokines and disease. Nat Immunol. 2001;2:108–115
- . Chemokine receptors: multifaceted therapeutic targets. Nat Rev Immunol. 2002;2:106–115
- . New anti-HIV agents and targets. Med Res Rev. 2002;22:531–565
- . Development and evaluation of pharmacological agents targeting chemokine receptors. Methods. 2003;29:369–375
- The chemokine system and CCR5 antagonists: potential in HIV treatment and other novel therapies. J Clin Pharm Ther. 2009;34:147–160
Financial disclosure: See Acknowledgments on page 318.
PII: S1083-8791(09)00586-2
doi: 10.1016/j.bbmt.2009.12.002
© 2010 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Biology of Blood and Marrow Transplantation
Volume 16, Issue 3
, Pages 311-319
, March 2010
