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Biology of Blood and Marrow Transplantation
Volume 16, Issue 5
, Pages 565-586
, May 2010
NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction
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- Low number of donor activating killer immunoglobulin-like receptors (KIR) genes but not KIR-ligand mismatch prevents relapse and improves disease-free survival in leukemia patients after in vivo T-cell depleted unrelated stem cell transplantation. Transplantation. 2006;82:1024–1030
- Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood. 2009;113:726–732
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- Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science. 2002;298:850–854
- Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood. 2005;105:3051–3057
- Safety and immunologic effects of IL-15 administration in nonhuman primates. Blood. 2009;114:2417–2426
- Expansion of highly cytotoxic human natural killer cells for cancer cell therapy. Cancer Res. 2009;69:4010–4017
- Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells. Cytotherapy. 2009;11:341–355
Financial disclosure: See Acknowledgments on page 581.
PII: S1083-8791(10)00060-1
doi: 10.1016/j.bbmt.2010.02.005
© 2010 American Society for Blood and Marrow Transplantation. All rights reserved.
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Biology of Blood and Marrow Transplantation
Volume 16, Issue 5
, Pages 565-586
, May 2010
