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Biology of Blood and Marrow Transplantation
Volume 17, Issue 1
, Pages 48-60
, January 2011
Combined Effects of Interleukin-7 and Stem Cell Factor Administration on Lymphopoiesis after Murine Bone Marrow Transplantation
References
- Long-term survival and late deaths after allogeneic bone marrow transplantation. N Engl J Med. 1999;341:14–21
- Late infections after allogeneic bone marrow transplantations: comparison of incidence in related and unrelated donor transplant recipients. Blood. 1995;86:3979–3986
- . Immunological reconstitution following hematopoietic stem cell transplantation. In: Thomas ED, Blume KG, Forman SJ editor. Hematopoietic Stem Cell Transplantation. 2nd ed. Oxford, UK: Blackwell; 1999;p. 704–711
- Changes in thymic function with age and during the treatment of HIV infection. Nature. 1998;396:690–695
- Radiosensitivity of thymic interleukin-7 production and thymopoiesis after bone marrow transplantation. Blood. 2001;98:1601–1606
- Age, thymopoiesis, and CD4+ T-cell regeneration after intensive chemotherapy. N Engl J Med. 1995;332:143–149
- Age-dependent incidence, time course, and consequences of thymic renewal in adults. J Clin Invest. 2005;115:930–939
- Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation. Blood. 2002;99:4592–4600
- Prevention of graft-versus-host disease by anti–IL-7R alpha antibody. Blood. 2007;110:2803–2810
- Interleukin 7 worsens graft-versus-host disease. Blood. 2002;100:2642–2649
- Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration. Blood. 2006;107:2453–2460
- Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation. Blood. 2001;97:1458–1466
- Comparison of immune reconstitution after unrelated and related T-cell–depleted bone marrow transplantation: effect of patient age and donor leukocyte infusions. Blood. 1999;93:467–480
- Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease. Blood. 2002;100:682–691
- Treatment of high-risk acute leukemia with T-cell–depleted stem cells from related donors with one fully mismatched HLA haplotype. N Engl J Med. 1998;339:1186–1193
- . Stem cell factor and hematopoiesis. Blood. 1997;90:1345–1364
- IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets. Int Immunol. 1989;169:707–716
- Early lymphocyte expansion is severely impaired in interleukin 7 receptor–deficient mice. J Exp Med. 1994;180:1955–1960
- . T lymphocyte development and function in dogs with X-linked severe combined immune deficiency. J Immunol. 1994;153:4006
- Interleukin 2 receptor γ chain mutation results in X-linked severe combined immune deficiency in humans. Cell. 1993;73:147
- Defective IL7R expression in T(−)B(+)NK(+) severe combined immunodeficiency. Nat Genet. 1998;20:394–397
- Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood. 1996;88:1887–1894
- IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation. Blood. 2001;97:1491–1497
- Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naïve T cell subsets. J Exp Med. 2008;205:1701–1714
- IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells. J Immunother. 2006;29:313–319
- Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity. 1995;3:313–319
- . Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. J Immunol. 1992;149:2281–2285
- Critical role for c-kit (CD117) in T cell lineage commitment and early thymocyte development in vitro. Eur J Immunol. 2006;36:526–532
- Interaction of the erythropoietin and stem-cell factor receptors. Nature. 1995;377:242–246
- Steel factor stimulates the serine/threonine phosphorylation of the interleukin-3 receptor. J Biol Chem. 1994;269:1677–1679
- Pro-thymocyte expansion by c-kit and the common cytokine receptor γ chain is essential for repertoire formation. Immunity. 1997;6:265–272
- Direct interaction between Kit and the interleukin-7 receptor. Blood. 2007;110:1840–1847
- Toyama A, Chung B, Brown J, et al. Essential roles for IL-7 and c-kit signaling pathways in fetal and post-natal thymopoiesis. Manuscript in preparation.
- Interleukin-7–engineered mesenchymal cells: in vitro effects on naïve T-cell population. Biol Blood Marrow Transplant. 2006;12:1250–1260
- Interleukin 7–engineered stromal cells: a new approach for hastening naïve T cell recruitment. Hum Gene Ther. 2005;16:752–764
- . Role of mesenchymal stem cells in hematopoietic stem cell transplantation. Curr Opin Hematol. 2000;7:358–363
- . Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors. Blood. 1994;83:3041–3051
- Mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res. 2008;68:6587–6597
- Steel factor (c-kit ligand) stimulates the in vitro growth of immature CD3−/CD4−/CD8− thymocytes: synergy with IL-7. Cells Immunol. 1994;157:118–131
- . Synergistic action of stem cell factor and interleukin-7 in a human immature T-cell line. Immunology. 1999;96:202–206
- CD34-expressing human thymocyte precursors proliferate in response to interleukin-7 but have lost myeloid differentiation potential. Blood. 1993;82:3675–3685
- Amplification of T cells from human cord blood in serum-deprived culture stimulated with stem cell factor, interleukin-7, and interleukin-2. Bone Marrow Transplant. 2003;31:713–723
- . The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection. Immunity. 1996;147–161
- Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat Immunol. 2003;4:866–873
- Commitment and development potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity. 2007;26:678–689
- . Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977–1984
- Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation. Blood. 2003;102:421–428
- In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells. Blood. 1993;82:445–455
- Dudl E, Chung B, Arber C, et al. Effects of common gamma and kit signals on lymphohematopoietic populations in vivo. Manuscript in preparation.
- Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro. Blood. 1994;84:1450–1456
- . The long road to the thymus: the generation, mobilization, and circulation of T-cell progenitors in mouse and man. Semin Immunopathol. 2008;30:371–382
- Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol. 2002;30:870–878
- . Mesenchymal stem cells in hematopoietic stem cell transplantation. Cytotherapy. 2009;11:503–515
- Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells. Leukemia. 2007;21:1733–1738
- . Mesenchymal stem cells: properties and role in clinical bone marrow transplantation. Curr Opin Immunol. 2006;18:586–591
- IL-7 is necessary for the development of experimental graft-versus-host disease. Biol Blood Marrow Transplant. 2008;14:16–27
Financial disclosure: See Acknowledgments on page 59.
PII: S1083-8791(10)00342-3
doi: 10.1016/j.bbmt.2010.07.027
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Biology of Blood and Marrow Transplantation
Volume 17, Issue 1
, Pages 48-60
, January 2011
