Biology of Blood and Marrow Transplantation
Volume 16, Issue 11 , Pages 1541-1548 , November 2010

Availability of Cord Blood Extends Allogeneic Hematopoietic Stem Cell Transplant Access to Racial and Ethnic Minorities

  • Juliet N. Barker

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
    • Corresponding Author InformationCorrespondence and reprint requests: Juliet N. Barker, MBBS (Hons), Department of Medicine, Sloan-Kettering Cancer Center, Box 259, 1275 York Ave, New York, NY 10065.
  • ,
  • Courtney E. Byam

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Nancy A. Kernan

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Sinda S. Lee

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Rebecca M. Hawke

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Kathleen A. Doshi

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Deborah S. Wells

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Glenn Heller

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • Esperanza B. Papadopoulos

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
  • ,
  • Andromachi Scaradavou

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
  • ,
  • James W. Young

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
  • ,
  • Marcel R.M. van den Brink

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York

Received 30 June 2010 ,Accepted 16 August 2010.

  • Image Result

    Comparison of ancestry composition of URD and CB transplant recipients and those without a graft. Greater than 50% of CB transplant recipients were non-European. Patients with African ancestry were th

    Comparison of ancestry composition of URD and CB transplant recipients and those without a graft. Greater than 50% of CB transplant recipients were non-European. Patients with African ancestry were the least likely to secure a suitable graft.

  • Image Result
    Comparison of transplant type or lack of graft for individual ancestry groups. URD transplantation predominantly serves Europeans. CB significantly extends transplant access to patients of eastern, so

    Comparison of transplant type or lack of graft for individual ancestry groups. URD transplantation predominantly serves Europeans. CB significantly extends transplant access to patients of eastern, southern, and mixed European ancestry, as well as Asian, African, white Hispanic, and mixed non-European patients.

 Financial disclosure: See Acknowledgments on page 1547.

PII: S1083-8791(10)00350-2

doi: 10.1016/j.bbmt.2010.08.011

Biology of Blood and Marrow Transplantation
Volume 16, Issue 11 , Pages 1541-1548 , November 2010