Biology of Blood and Marrow Transplantation
Volume 16, Issue 11 , Pages 1541-1548 , November 2010

Availability of Cord Blood Extends Allogeneic Hematopoietic Stem Cell Transplant Access to Racial and Ethnic Minorities

  • Juliet N. Barker

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
    • Corresponding Author InformationCorrespondence and reprint requests: Juliet N. Barker, MBBS (Hons), Department of Medicine, Sloan-Kettering Cancer Center, Box 259, 1275 York Ave, New York, NY 10065.
    • ,
  • Courtney E. Byam

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Nancy A. Kernan

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Sinda S. Lee

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Rebecca M. Hawke

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Kathleen A. Doshi

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Deborah S. Wells

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Glenn Heller

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • Esperanza B. Papadopoulos

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Andromachi Scaradavou

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • ,
  • James W. Young

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York
    • ,
  • Marcel R.M. van den Brink

      Affiliations

    • Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York
    • Weill Medical College of Cornell University, New York, New York

Received 30 June 2010 ,Accepted 16 August 2010.

References 

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  13. Kurtzberg J, Prasad VK, Carter SL, et al. Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood. 2008;112:4318–4327
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  17. Barker JN, Abboud M, Rice RD, et al. A “no-wash” albumin-dextran dilution strategy for cord blood unit thaw: high rate of engraftment and a low incidence of serious infusion reactions. Biol Blood Marrow Transplant. 2009;15:1596–1602
  18. Ponce D, Zheng J, Gonzales AM, et al. Disease-free survival after cord blood transplantation is not different to that after related or unrelated donor transplantation in patients with hematologic malignancies. Blood. 2009;114:Abstract 906
  19. Brunstein CG, Gutman JA, DeFor TE, et al. Reduced relapse and similar progression-free survival after double umbilical cord blood transplantation (DUCBT): comparison of outcomes between sibling, unrelated adult and unrelated DUCB hematopoietic stem cell donors. Blood. 2009;114:276
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  24. Hurley CK, Fernandez-Vina M, Hildebrand WH, et al. A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol. 2007;68:30–40
  25. Barker JN, Krepski TP, DeFor TE, et al. Searching for unrelated donor hematopoietic stem cells: availability and speed of umbilical cord blood versus bone marrow. Biol Blood Marrow Transplant. 2002;8:257–260
  26. Santos F. Mayor orders NY to expand language help. NY Times. 2008;
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 Financial disclosure: See Acknowledgments on page 1547.

PII: S1083-8791(10)00350-2

doi: 10.1016/j.bbmt.2010.08.011

Biology of Blood and Marrow Transplantation
Volume 16, Issue 11 , Pages 1541-1548 , November 2010

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