Biology of Blood and Marrow Transplantation
Volume 17, Issue 5 , Pages 723-728 , May 2011

Unrelated Donor Bone Marrow Transplantation for Myelodysplastic Syndrome in Children

  • Paul Woodard

      Affiliations

    • Amgen, Thousand Oaks, California
  • ,
  • Paul A. Carpenter

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
  • ,
  • Stella M. Davies

      Affiliations

    • Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
  • ,
  • Thomas G. Gross

      Affiliations

    • Nationwide Children’s Hospital, Columbus, Ohio
  • ,
  • Wensheng He

      Affiliations

    • Center for International Blood and Marrow Transplant Research, Milwaukee, Wisconsin
  • ,
  • Mei-Jie Zhang

      Affiliations

    • Center for International Blood and Marrow Transplant Research, Milwaukee, Wisconsin
  • ,
  • Biljana N. Horn

      Affiliations

    • University of California San Francisco Medical Center, San Francisco, California
  • ,
  • David A. Margolis

      Affiliations

    • Children’s Hospital of Wisconsin, Milwaukee, Wisconsin
  • ,
  • John P. Perentesis

      Affiliations

    • Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
  • ,
  • Jean E. Sanders

      Affiliations

    • Fred Hutchinson Cancer Research Center, Seattle, Washington
  • ,
  • Kirk R. Schultz

      Affiliations

    • British Columbia’s Children’s Hospital, UBC, Vancouver, British Columbia, Canada
  • ,
  • Adriana Seber

      Affiliations

    • Instituto de Oncologia Pediatrica, Sao Paulo, Brazil
  • ,
  • William G. Woods

      Affiliations

    • Children’s Healthcare of Atlanta at Egleston, Aflac Cancer Center and Blood Disorders Services, Atlanta, Georgia
  • ,
  • Mary Eapen

      Affiliations

    • Center for International Blood and Marrow Transplant Research, Milwaukee, Wisconsin
    • Corresponding Author InformationCorrespondence and reprint requests: Mary Eapen, MBBS, MS, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Suite C 5500, Milwaukee, WI 53226.

Received 16 July 2010 ,Accepted 18 August 2010.

  • Image Result

    The 8-year probabilities of recurrent disease after BMT: 4% when transplantation was performed for RC, 23% when transplantation was performed for RAEB, and 29% for when transplantation was performed f

    The 8-year probabilities of recurrent disease after BMT: 4% when transplantation was performed for RC, 23% when transplantation was performed for RAEB, and 29% for when transplantation was performed for RAEB-T.

  • Image Result
    (A) The 8-year probabilities of disease-free survival after BMT: 57% for patients received matched BMT (matched at HLA A, B, C, DRB1), 33% for patients received mismatched BMT. (B) The 8-year probabil

    (A) The 8-year probabilities of disease-free survival after BMT: 57% for patients received matched BMT (matched at HLA A, B, C, DRB1), 33% for patients received mismatched BMT. (B) The 8-year probabilities of disease-free survival after BMT: 51% when transplantation was performed for RC, 35% when transplantation was performed for RAEB, and 29% for when transplantation was performed for RAEB-T.

 Financial disclosure: See Acknowledgments on page 727.

PII: S1083-8791(10)00365-4

doi: 10.1016/j.bbmt.2010.08.016

Biology of Blood and Marrow Transplantation
Volume 17, Issue 5 , Pages 723-728 , May 2011