Biology of Blood and Marrow Transplantation
Volume 17, Issue 5 , Pages 729-736 , May 2011

Cost and Clinical Analysis of Autologous Hematopoietic Stem Cell Mobilization with G-CSF and Plerixafor Compared to G-CSF and Cyclophosphamide

  • Paul Shaughnessy

      Affiliations

    • Texas Transplant Institute, San Antonio, Texas
    • Corresponding Author InformationCorrespondence and reprint requests: Paul Shaughnessy, MD, Texas Transplant Institute, 7711 Louis Pasteur, Suite 704, San Antonio, TX 78229.
  • ,
  • Miguel Islas-Ohlmayer

      Affiliations

    • Texas Transplant Institute, San Antonio, Texas
  • ,
  • Julie Murphy

      Affiliations

    • Rocky Mountain Blood and Marrow Transplant Program, Denver, Colorado
  • ,
  • Maureen Hougham

      Affiliations

    • Texas Transplant Institute, San Antonio, Texas
  • ,
  • Jill MacPherson

      Affiliations

    • Texas Transplant Institute, San Antonio, Texas
  • ,
  • Kurt Winkler

      Affiliations

    • Texas Transplant Institute, San Antonio, Texas
  • ,
  • Matthew Silva

      Affiliations

    • Massachusetts College of Pharmacy and Health Sciences, Worcester, Massachusetts
  • ,
  • Michael Steinberg

      Affiliations

    • Massachusetts College of Pharmacy and Health Sciences, Worcester, Massachusetts
  • ,
  • Jeffrey Matous

      Affiliations

    • Rocky Mountain Blood and Marrow Transplant Program, Denver, Colorado
  • ,
  • Sheryl Selvey

      Affiliations

    • Massachusetts College of Pharmacy and Health Sciences, Worcester, Massachusetts
  • ,
  • Michael Maris

      Affiliations

    • Rocky Mountain Blood and Marrow Transplant Program, Denver, Colorado
  • ,
  • Peter A. McSweeney

      Affiliations

    • Rocky Mountain Blood and Marrow Transplant Program, Denver, Colorado

Received 21 July 2010 ,Accepted 23 August 2010.

  • Image Result

    Chemotherapy mobilization dosing regimen (control patients).

    Chemotherapy mobilization dosing regimen (control patients).

  • Image Result

    Perixafor mobilization dosing regimen (EAP study patients).

    Perixafor mobilization dosing regimen (EAP study patients).

  • Image Result

    Total median costs associated with successive days to mobilization. The total cost of mobilization for each patient was determined through the indicated day of apheresis and medians were calcultaed fo

    Total median costs associated with successive days to mobilization. The total cost of mobilization for each patient was determined through the indicated day of apheresis and medians were calcultaed for each group in each day of apheresis. The upper boundary of the box represents the 75th percentile and the lower boundary the 25th percentile; the line represents the median for each group.

 Financial disclosure: See Acknowledgments on page 736.

PII: S1083-8791(10)00367-8

doi: 10.1016/j.bbmt.2010.08.018

Biology of Blood and Marrow Transplantation
Volume 17, Issue 5 , Pages 729-736 , May 2011