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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Of Genes, Blocks and Haplotypes
DOI: 10.1016/j.bbmt.2012.01.016
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Effie W. Petersdorf
|
Discussion
(In Press Accepted Manuscript)
|
30 January 2012 |
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A Meta-Analysis of Unrelated Donor Umbilical Cord Blood Transplantation versus Unrelated Donor Bone Marrow Transplantation in Acute Leukemia Patients
DOI: 10.1016/j.bbmt.2012.01.015
Abstract: Umbilical cord blood has emerged as an alternative stem cell source to bone marrow or peripheral blood stem cells. Unrelated donor cord blood transplantation (UCBT) is also potentially curat...
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Haoran Zhang,
Junmin Chen,
Wenzhong Que
|
Review article
(In Press Accepted Manuscript)
|
30 January 2012 |
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Risk Factors for Molecular Detection of Adenovirus in Pediatric Hematopoietic Stem Cell Transplant Recipients
DOI: 10.1016/j.bbmt.2012.01.013
Abstract: Adenovirus (AdV) infections are a major cause of morbidity and mortality in hematopoietic stem cell transplant HSCT) patients. To evaluate the use of molecular AdV testing in HSCT at our ins...
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Theresa Watson,
David MacDonald,
Xiaoyan Song,
Kira Bromwich,
Joseph Campos,
Jane Sande,
Roberta L. DeBiasi
et al.
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Full-length article
(In Press Accepted Manuscript)
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25 January 2012 |
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Rapid Thymic Reconstitution Following Bone Marrow Transplantation in Neonatal Mice is VEGF-Dependent
DOI: 10.1016/j.bbmt.2012.01.006
Abstract: Age-related differences in thymic function influence the rapidity of T cell reconstitution following hematopoietic stem cell transplantation (HSCT). In adults, thymic reconstitution is delay...
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Andrew R. Cuddihy,
Batul T. Suterwala,
Shundi Ge,
Lisa A. Kohn,
Julie Jang,
Jacob Andrade,
Xiaoyan Wang,
Gay M. Crooks
et al.
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Full-length article
(In Press Accepted Manuscript)
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25 January 2012 |
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Evaluation of minimal residual disease by real-time quantitative PCR of Wilms´ tumor 1 (WT1) expression in patients with acute myeloid leukemia after allogeneic stem cell transplantation. Correlation with flow cytometry and chimerism
DOI: 10.1016/j.bbmt.2012.01.012
Abstract: Background: Relapse remains the main cause of treatment failure in acute myeloid leukemia (AML) after allogeneic hemopoietic stem cell transplantation (SCT). WT1 has been reported to be over...
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Mi Kwon,
Carolina Martínez-Laperche,
María Infante,
Fernando Carretero,
Pascual Balsalobre,
David Serrano,
Jorge Gayoso,
Ana Pérez-Corral,
Javier Anguita,
Jose Luis Díez-Martín,
Ismael Buño
et al.
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Full-length article
(In Press Accepted Manuscript)
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25 January 2012 |
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The graft-versus-tumor effect according to the type of graft-versus-host disease defined by NIH consensus criteria and the associated outcomes
DOI: 10.1016/j.bbmt.2012.01.010
Abstract: The impact of graft-versus-host disease (GVHD) by the NIH consensus criteria (NCC) on survival has rarely been investigated with a large cohort of patients with GVHD presenting before and af...
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Byung-Sik Cho,
Sung-Eun Lee,
Hae-Hiang Song,
Ju-Hyoung Lee,
Seung-Ah Yahng,
Ki-Seong Eom,
Yoo-Jin Kim,
Hee-Je Kim,
Seok Lee,
Chang-Ki Min,
Seok-Goo Cho,
Dong-Wook Kim,
Jong-Wook Lee,
Woo-Sung Min,
Chong-Won Park
et al.
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Full-length article
(In Press Accepted Manuscript)
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18 January 2012 |
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Systematic review of randomized controlled trials of hematopoietic stem cell mobilization strategies for autologous transplantation for hematologic malignancies
DOI: 10.1016/j.bbmt.2012.01.008
Abstract: Background: Collection of adequate hematopoietic stem cells (HSCs) is necessary for successful autologous transplantation, however a proportion of patients fail to collect the minimum number...
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Dawn Sheppard,
Christopher Bredeson,
David Allan,
Jason Tay
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Full-length article
(In Press Accepted Manuscript)
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18 January 2012 |
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Intermediate- versus low-dose cyclophosphamide and granulocyte colony stimulating factor for peripheral blood stem cell mobilization in multiple myeloma patients treated with novel induction therapies
DOI: 10.1016/j.bbmt.2012.01.005
Abstract: Peripheral blood progenitor cell (PBPC) mobilization with intermediate-dose cyclophosphamide (ID-CY) and G-CSF has been shown to be more efficacious, albeit more toxic than low-dose CY (LD-C...
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Mehdi Hamadani,
S Thomas Kochuparambil,
Salman Osman,
Aaron Cumpston,
Sonia Leadmon,
Pamela Bunner,
Kathy Watkins,
Devi Morrison,
Ethan Speir,
David DeRemer,
Vamsi Kota,
Anand Jillella,
Michael Craig,
Farrukh Awan
et al.
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Full-length article
(In Press Accepted Manuscript)
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16 January 2012 |
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Polymorphisms in the immunoregulatory genes are associated with hematopoietic recovery and increased susceptibility to bacterial infections in patients with thalassaemia major undergoing matched related hematopoietic stem cell transplantation (HSCT)
DOI: 10.1016/j.bbmt.2012.01.011
Abstract: In this study the impact of polymorphisms in the genes of pro-inflammatory (IL-β, TNF-α, IL-6, IFN-γ), anti-inflammatory (TGF-β, IL-10, IL-Ra) and other immunoregulatory factors (FcγRIIa, NO...
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Shanmugaapriya Sellathamby,
Kavitha M. Lakshmi,
Marc Busson,
Auro Viswabandya,
Biju George,
Vikram Mathews,
Mammen Chandy,
Dominique Charron,
Rajagopal Krishnamoorthy,
Ryad Tamouza,
Alok Srivastava
et al.
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Full-length article
(In Press Accepted Manuscript)
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16 January 2012 |
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National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: The Need for Pediatric-Specific Long-Term Follow-up Guidelines
DOI: 10.1016/j.bbmt.2012.01.003
Existing standards for screening and management of late effects occurring in children who have undergone hematopoietic cell transplantation (HCT) include recommendations from pediatric cancer networks...
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Michael A. Pulsipher,
Roderick Skinner,
George B. McDonald,
Sangeeta Hingorani,
Saro H. Armenian,
Kenneth R. Cooke,
Clarisa Gracia,
Anna Petryk,
Smita Bhatia,
Nancy Bunin,
Michael L. Nieder,
Christopher C. Dvorak,
Lillian Sung,
Jean E. Sanders,
Joanne Kurtzberg,
K. Scott Baker
et al.
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Review article
(In Press Uncorrected Proof)
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16 January 2012 |
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Decreased serum testosterone levels in long-term adult survivors with fatty liver after childhood stem cell transplant
DOI: 10.1016/j.bbmt.2012.01.004
Abstract: Fatty liver and male gonadal dysfunction are potential late effects of therapy in adult survivors treated with stem cell transplantation (SCT) in childhood. Obesity and metabolic syndrome ar...
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Hiromi Hyodo,
Hiroyuki Ishiguro,
Yuichiro Tomita,
Hiromitsu Takakura,
Takashi Koike,
Takashi Shimizu,
Tsuyoshi Morimoto,
Hiromasa Yabe,
Miharu Yabe,
Sei-ichiro Kojima,
Koichi Shiraishi,
Takashi Minemura,
Shunichi Kato
et al.
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Full-length article
(In Press Accepted Manuscript)
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16 January 2012 |
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Pre-Transplant Therapy with Azacitidine Versus Induction Chemotherapy and Post-Transplant Outcome in Patients with MDS
DOI: 10.1016/j.bbmt.2012.01.009
Abstract: While allogeneic hematopoietic cell transplantation (HCT) has proven curative potential for myelodysplastic syndrome (MDS), relapse after HCT remains a problem. Pre-transplant cytoreduction ...
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Aaron T. Gerds,
Ted A. Gooley,
Elihu H. Estey,
Frederick R. Appelbaum,
H. Joachim Deeg,
Bart L. Scott
et al.
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Full-length article
(In Press Accepted Manuscript)
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16 January 2012 |
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To Induce, or Not to Induce, that is the (Still Unanswered) Question
DOI: 10.1016/j.bbmt.2012.01.002
A 41 year old man presents to you with pancytopenia. He is asymptomatic except for mild fatigue. Liver, pulmonary, and kidney functions are normal. Bone marrow biopsy is normocellular with multilineag...
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Robert J. Soiffer
|
Discussion
(In Press Uncorrected Proof)
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13 January 2012 |
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The Use of Back-up Units to Enhance the Safety of Unrelated Donor Cord Blood Transplantation
DOI: 10.1016/j.bbmt.2011.12.588
The inability to obtain additional stem cells is a disadvantage of unrelated donor cord blood transplantation (CBT). Moreover, in the event of problems with unit shipment, compromised unit quality, th...
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Doris M. Ponce,
Marissa Lubin,
Anne Marie Gonzales,
Courtney Byam,
Deborah Wells,
Rosanna Ferrante,
Glenn Heller,
Sergio Giralt,
Esperanza B. Papadopoulos,
Nancy A. Kernan,
Andromachi Scaradavou,
Juliet N. Barker
et al.
|
Short communication
(In Press Uncorrected Proof)
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13 January 2012 |
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Prophylactic and Preemptive Therapy with Dasatinib after Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
DOI: 10.1016/j.bbmt.2011.12.587
|
Giovanni Caocci,
Adriana Vacca,
Antonio Ledda,
Francesca Murgia,
Eugenia Piras,
Marianna Greco,
Marcella Arras,
Sandra Atzeni,
Giorgio La Nasa,
Roberto Littera
et al.
|
Correspondence
(In Press Uncorrected Proof)
|
11 January 2012 |
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Cotransplantation of Ex Vivo Expanded and Unexpanded Cord Blood Units in Immunodeficient Mice Using Insulin Growth Factor Binding Protein-2–Augmented Mesenchymal Cell Cocultures
DOI: 10.1016/j.bbmt.2012.01.001
Ex vivo expansion of cord blood (CB) hematopoietic stem cells and cotransplantation of 2 CB units (CBUs) could enhance the applicability of CB transplantation in adult patients. We report an immunodef...
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Li Ming Ong,
Xiubo Fan,
Pat Pak Yan Chu,
Florence Pik Hoon Gay,
Sudipto Bari,
Justina May Lynn Ang,
Zhihong Li,
Jianzhu Chen,
Sai Kiang Lim,
Ralph Milford Bunte,
William Ying Khee Hwang
et al.
|
Full-length article
(In Press Uncorrected Proof)
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11 January 2012 |
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IL-2–Targeted Therapy Ameliorates the Severity of Graft-versus-Host Disease: Ex Vivo Selective Depletion of Host-Reactive T Cells and In Vivo Therapy
DOI: 10.1016/j.bbmt.2011.11.016
T cell depletion prevents graft-versus-host disease (GVHD) but also removes T cell-mediated support of hematopoietic cell engraftment. A chimeric molecule composed of IL-2 and caspase-3 (IL2-cas) has ...
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Shai Yarkoni,
Tatyana B. Prigozhina,
Shimon Slavin,
Nadir Askenasy
|
Full-length article
(In Press Uncorrected Proof)
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05 January 2012 |
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Peripheral Blood CD34+ Cell Enumeration as a Predictor of Apheresis Yield: An Analysis of More Than 1000 Collections
DOI: 10.1016/j.bbmt.2011.10.002
The role of the peripheral blood (PB) CD34+ cell count in predicting the CD34+ cell yield in hematopoietic progenitor cell apheresis (HPC-A) collections is well established. However, sometimes unexpec...
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Peter Gambell,
Kirsten Herbert,
Michael Dickinson,
Kerrie Stokes,
Mathias Bressel,
Dominic Wall,
Simon Harrison,
H. Miles Prince
et al.
|
Full-length article
(In Press Uncorrected Proof)
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05 January 2012 |
|
In Vitro Evaluation of Graft-versus-Graft Alloreactivity as a Tool to Identify the Predominant Cord Blood Unit before Double Cord Blood Transplantation
DOI: 10.1016/j.bbmt.2011.12.586
The transplantation of 2 cord blood (CB) units obtained from unrelated donors (double CBT) is an effective strategy for adult patients with hematologic malignancies. Sustained hematopoiesis after doub...
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Antonia Moretta,
Gabriella Andriolo,
Daniela Lisini,
Miryam Martinetti,
Annamaria Pasi,
Paolo Rebulla,
Davide Soligo,
Rosaria Giordano,
Lorenza Lazzari,
Rita Maccario
et al.
|
Full-length article
(In Press Uncorrected Proof)
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05 January 2012 |
|
Role of Cytotoxic Therapy with Hematopoietic Stem Cell Transplantation in the Treatment of Pediatric Acute Lymphoblastic Leukemia: Update of the 2005 Evidence-Based Review
DOI: 10.1016/j.bbmt.2011.12.585
Clinical research published since the first evidence-based review on the role of hematopoietic stem cell transplantation (SCT) in the treatment of pediatric acute lymphoblastic leukemia (ALL) is prese...
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Denise M. Oliansky,
Bruce Camitta,
Paul Gaynon,
Michael L. Nieder,
Susan K. Parsons,
Michael A. Pulsipher,
Hildy Dillon,
Thomas A. Ratko,
Donna Wall,
Philip L. McCarthy,
Theresa Hahn
et al.
|
Review article
(In Press Uncorrected Proof)
|
03 January 2012 |
|
Early Human Herpesvirus Type 6 Reactivation after Allogeneic Stem Cell Transplantation: A Large-Scale Clinical Study
DOI: 10.1016/j.bbmt.2011.12.579
This study investigated the impact of human herpesvirus type 6 (HHV6) reactivation within 100 days of allogeneic stem cell transplantation (allo-SCT) on patient outcomes. HHV6 plasma loads were monito...
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Rémy Dulery,
Julia Salleron,
Anny Dewilde,
Julien Rossignol,
Eileen M. Boyle,
Julie Gay,
Eva de Berranger,
Valerie Coiteux,
Jean-Pierre Jouet,
Alain Duhamel,
Ibrahim Yakoub-Agha
et al.
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Full-length article
(In Press Uncorrected Proof)
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03 January 2012 |
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Graft-versus-Host Disease Prophylaxis: Does Drug Dosage Matter?
DOI: 10.1016/j.bbmt.2011.12.583
Acute graft-versus-host disease (aGVHD) is a common immunologic complication which occurs in 40% to 50% of the recipients of allogeneic stem cell transplantation (SCT). The immunologic events leading ...
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Gérard Socié
|
Discussion
(In Press Uncorrected Proof)
|
26 December 2011 |
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Sequential Bortezomib, Dexamethasone, and Thalidomide Maintenance Therapy after Single Autologous Peripheral Stem Cell Transplantation in Patients with Multiple Myeloma
DOI: 10.1016/j.bbmt.2011.12.580
We report feasibility and response results of a phase II study investigating prolonged weekly bortezomib and dexamethasone followed by thalidomide and dexamethasone as maintenance therapy after single...
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Firoozeh Sahebi,
Paul H. Frankel,
Len Farol,
Amrita Y. Krishnan,
Ji-lian Cai,
George Somlo,
Sandra H. Thomas,
Eunicia Reburiano,
Leslie L. Popplewell,
Pablo M. Parker,
Ricardo T. Spielberger,
Neil M. Kogut,
Chatchada Karanes,
Myo Htut,
Christopher Ruel,
Lupe Duarte,
Joyce L. Murata-Collins,
Stephen J. Forman
et al.
|
Short communication
(In Press Uncorrected Proof)
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26 December 2011 |
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Outcome of Lower-Intensity Allogeneic Transplantation in Non-Hodgkin Lymphoma after Autologous Transplantation Failure
DOI: 10.1016/j.bbmt.2011.12.581
We studied the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) after lower-intensity conditioning regimens (reduced-intensity conditioning [RIC] and nonmyeloablative [NST]) i...
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César O. Freytes,
Mei-Jie Zhang,
Jeanette Carreras,
Linda J. Burns,
Robert Peter Gale,
Luis Isola,
Miguel-Angel Perales,
Matthew Seftel,
Julie M. Vose,
Alan M. Miller,
John Gibson,
Thomas G. Gross,
Philip A. Rowlings,
David J. Inwards,
Santiago Pavlovsky,
Rodrigo Martino,
David I. Marks,
Gregory A. Hale,
Sonali M. Smith,
Harry C. Schouten,
Simon Slavin,
Thomas R. Klumpp,
Hillard M. Lazarus,
Koen van Besien,
Parameswaran N. Hari
et al.
|
Full-length article
(In Press Uncorrected Proof)
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26 December 2011 |
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High Incidence of Radiation-Induced Cavernous Hemangioma in Long-Term Survivors Who Underwent Hematopoietic Stem Cell Transplantation with Radiation Therapy during Childhood or Adolescence
DOI: 10.1016/j.bbmt.2011.12.582
Radiation-induced cavernous hemangioma (RICH) is a late complication of cerebral radiation therapy. Long-term survivors of hematopoietic stem cell transplantation (HSCT) who received radiation therapy...
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Takashi Koike,
Noriharu Yanagimachi,
Hiroyuki Ishiguro,
Hiromasa Yabe,
Miharu Yabe,
Tsuyoshi Morimoto,
Takashi Shimizu,
Hiromitsu Takakura,
Shunichi Kato
et al.
|
Full-length article
(In Press Uncorrected Proof)
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26 December 2011 |
|
Maximally Tolerated Busulfan Systemic Exposure in Combination with Fludarabine as Conditioning before Allogeneic Hematopoietic Cell Transplantation
DOI: 10.1016/j.bbmt.2011.12.584
Systemic exposure to high-dose busulfan has been correlated with efficacy and toxicity after hematopoietic cell transplantation for malignancy. We used the area under the concentration-time curve (AUC...
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Janelle B. Perkins,
Jongphil Kim,
Claudio Anasetti,
Hugo F. Fernandez,
Lia E. Perez,
Ernesto Ayala,
Mohamed A. Kharfan-Dabaja,
Marcie R. Tomblyn,
Daniel M. Sullivan,
Joseph A. Pidala,
Teresa L. Field
et al.
|
Full-length article
(In Press Uncorrected Proof)
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26 December 2011 |
|
High White Blood Cell Concentration in the Peripheral Blood Stem Cell Product Can Induce Seizures during Infusion of Autologous Peripheral Blood Stem Cells
DOI: 10.1016/j.bbmt.2011.12.500
Seizures as a complication of the infusion of autologous peripheral blood stem cells (PBSC) are rare. Seizures during infusion of autologous PBSC in 3 of our patients prompted us to review our cell th...
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Carlos Bachier,
Josh Potter,
Grant Potter,
Rominna Sugay,
Paul Shaughnessy,
Kawah Chan,
Veronica Jude,
Renee Madden,
Charles F. LeMaistre
et al.
|
Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
|
Everolimus in Combination with Cyclosporin A as Pre- and Posttransplantation Immunosuppressive Therapy in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.12.522
Everolimus (RAD001) is an mTOR inhibitor that has been successfully used as an immunosuppressant in solid-organ transplantation. Data in allogeneic hematopoietic stem cell transplantation (HSCT) is li...
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Christian Junghanss,
Susanne Rathsack,
Rainer Wacke,
Volker Weirich,
Heike Vogel,
Bernd Drewelow,
Sabrina Mueller,
Simone Altmann,
Mathias Freund,
Sandra Lange
et al.
|
Full-length article
(In Press Uncorrected Proof)
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19 December 2011 |
|
Inhibition of Cathepsin S Reduces Allogeneic T Cell Priming but Not Graft-versus-Host Disease Against Minor Histocompatibility Antigens
DOI: 10.1016/j.bbmt.2011.11.027
Cathepsin (Cathepsin) S, L, and B proteases mediate antigen presentation on major histocompatibility complex (MHC) class II by degrading the invariant chain Ii, which blocks peptide loading. The abili...
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Hisaki Fujii,
Sabine M. Ivison,
Hiromi Shimizu,
Ryosuke Kajiwara,
Amina Kariminia,
Matthew Yan,
Jan P. Dutz,
Kirk R. Schultz
et al.
|
Full-length article
(In Press Uncorrected Proof)
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16 December 2011 |
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Genetic Variation in Donor CTLA-4 Regulatory Region is a Strong Predictor of Outcome after Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies
DOI: 10.1016/j.bbmt.2011.12.518
Relapse remains a major cause of death after allogeneic hematopoietic cell transplantation (allo-HCT). Graft-versus-tumor effect is primarily mediated by donor T cells. Cytotoxic T lymphocyte antigen-...
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Madan Jagasia,
William B. Clark,
Kristin D. Brown-Gentry,
Dana C. Crawford,
Kang-Hsien Fan,
Heidi Chen,
Adetola Kassim,
John P. Greer,
Brian G. Engelhardt,
Bipin N. Savani
et al.
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Full-length article
(In Press Uncorrected Proof)
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15 December 2011 |
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Recommended Screening and Preventive Practices for Long-Term Survivors after Hematopoietic Cell Transplantation
DOI: 10.1016/j.bbmt.2011.12.519
Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, intro...
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Navneet S. Majhail,
J. Douglas Rizzo,
Stephanie J. Lee,
Mahmoud Aljurf,
Yoshiko Atsuta,
Carmem Bonfim,
Linda J. Burns,
Naeem Chaudhri,
Stella Davies,
Shinichiro Okamoto,
Adriana Seber,
Gerard Socie,
Jeff Szer,
Maria Teresa Van Lint,
John R. Wingard,
Andre Tichelli,
Center for International Blood and Marrow Transplant Research (CIBMTR),
American Society for Blood and Marrow Transplantation (ASBMT),
European Group for Blood and Marrow Transplantation (EBMT),
Asia-Pacific Blood and Marrow Transplantation Group (APBMT),
Bone Marrow Transplant Society of Australia and New Zealand (BMTSANZ),
East Mediterranean Blood and Marrow Transplantation Group (EMBMT),,
Sociedade Brasileira de Transplante de Medula Ossea (SBTMO)
et al.
|
Review article
(In Press Uncorrected Proof)
|
15 December 2011 |
|
Successful Remission Rates and Survival after Lymphodepleting Chemotherapy and Donor Lymphocyte Infusion for Relapsed Hematologic Malignancies Postallogeneic Hematopoietic Cell Transplantation
DOI: 10.1016/j.bbmt.2011.11.030
Few therapeutic strategies exist for hematologic malignancies relapsing post allogeneic hematopoietic cell transplantation. We present outcomes on 35 patients with nonchronic myelogenous leukemia (CML...
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Erica D. Warlick,
Todd DeFor,
Bruce R. Blazar,
Linda Burns,
Michael R. Verneris,
Celalettin Ustun,
Daniel J. Weisdorf,
Jeffrey S. Miller
et al.
|
Short communication
(In Press Corrected Proof)
|
12 December 2011 |
|
Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for Subacute Pulmonary Dysfunction Following Allogeneic Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.11.031
Subacute lung disease, manifested as either obstructive (OLD) or restrictive (RLD) lung dysfunction, is a common complication following allogeneic stem cell transplantation. In each case, therapeutic ...
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Gregory A. Yanik,
Shin Mineishi,
John E. Levine,
Carrie L. Kitko,
Eric S. White,
Mark T. Vander Lugt,
Andrew C. Harris,
Thomas Braun,
Kenneth R. Cooke
et al.
|
Full-length article
(In Press Uncorrected Proof)
|
12 December 2011 |
|
Natural Killer Cell Differentiation from Hematopoietic Stem Cells: A Comparative Analysis of Heparin- and Stromal Cell–Supported Methods
DOI: 10.1016/j.bbmt.2011.11.023
Natural killer (NK) cells differentiated from hematopoietic stem cells (HSCs) may have significant clinical benefits over NK cells from adult donors, including the ability to choose alloreactive donor...
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Steven A. Dezell,
Yong-Oon Ahn,
Jan Spanholtz,
Hongbo Wang,
Matthew Weeres,
Scott Jackson,
Sarah Cooley,
Harry Dolstra,
Jeffrey S. Miller,
Michael R. Verneris
et al.
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Full-length article
(In Press Uncorrected Proof)
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08 December 2011 |
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Tandem Autologous–Allogeneic Nonmyeloablative Sibling Transplantation in Relapsed Follicular Lymphoma Leads to Impressive Progression-Free Survival with Minimal Toxicity
DOI: 10.1016/j.bbmt.2011.11.028
Autologous stem cell transplantation (ASCT) prolongs survival in patients with relapsed follicular lymphoma. ASCT is usually not curative, however. Myeloablative allogeneic transplantation has produce...
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Sandra Cohen,
Thomas Kiss,
Silvy Lachance,
Denis Claude Roy,
Guy Sauvageau,
Lambert Busque,
Imran Ahmad,
Jean Roy
et al.
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Full-length article
(In Press Uncorrected Proof)
|
08 December 2011 |
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T Cell-Depleted Partial Matched Unrelated Donor Transplant for Advanced Myeloid Malignancy: KIR Ligand Mismatch and Outcome
DOI: 10.1016/j.bbmt.2011.11.024
To evaluate the applicability of high-dose conditioning, CD34 selection, and enhanced natural killer (NK) cell alloreactivity reported as promising after haploidentical transplantation, we tested the ...
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Daniel Weisdorf,
Sarah Cooley,
Steven Devine,
Todd Fehninger,
John DiPersio,
Claudio Anasetti,
Edmund Waller,
David Porter,
Sherif Farag,
William Drobyski,
Todd Defor,
Michael Haagenson,
Julie Curtsinger,
Jeffrey Miller
et al.
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Full-length article
(In Press Uncorrected Proof)
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08 December 2011 |
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Important Drug Interactions in Hematopoietic Stem Cell Transplantation: What Every Physician Should Know
DOI: 10.1016/j.bbmt.2011.11.029
Abstract: Morbidity is increased in patients undergoing hematopoietic stem cell transplantation when drug–drug interactions lead to unexpected outcomes. These interactions occur as a result of exposur...
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Brett Glotzbecker,
Christine Duncan,
Edwin Alyea,
Bonnie Campbell,
Robert Soiffer
et al.
|
Review article
(In Press Uncorrected Proof)
|
08 December 2011 |
|
Highly Variable Pharmacokinetics of Once-Daily Intravenous Busulfan When Combined with Fludarabine in Pediatric Patients: Phase I Clinical Study for Determination of Optimal Once-Daily Busulfan Dose Using Pharmacokinetic Modeling
DOI: 10.1016/j.bbmt.2011.11.025
Busulfan has a narrow therapeutic range, and in children, pharmacokinetic variability has been found to be high even after the use of intravenous (i.v.) busulfan. Recently, a reduced toxicity myeloabl...
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Ji Won Lee,
Hyoung Jin Kang,
Seung Hwan Lee,
Kyung-Sang Yu,
Nam Hee Kim,
Yen Ju Yuk,
Mi Kyoung Jang,
Eun Jong Han,
Hyery Kim,
Sang Hoon Song,
Kyung Duk Park,
Hee Young Shin,
In-Jin Jang,
Hyo Seop Ahn
et al.
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Full-length article
(In Press Uncorrected Proof)
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08 December 2011 |
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Alternate Donor Hematopoietic Cell Transplantation (HCT) in Non-Hodgkin Lymphoma Using Lower Intensity Conditioning: A Report from the CIBMTR
DOI: 10.1016/j.bbmt.2011.11.026
We analyzed the outcomes of 248 (61% male) adult recipients of HLA-matched unrelated and HLA-mismatched related donor hematopoietic cell transplantation (HCT) for non-Hodgkin lymphoma (NHL) after redu...
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Gregory A. Hale,
Smriti Shrestha,
Jennifer Le-Rademacher,
Linda J. Burns,
John Gibson,
David J. Inwards,
Cesar O. Freytes,
Brian J. Bolwell,
Jack W. Hsu,
Shimon Slavin,
Luis Isola,
David A. Rizzieri,
Robert Peter Gale,
Ginna G. Laport,
Silvia Montoto,
Hillard M. Lazarus,
Parameswaran N. Hari
et al.
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Full-length article
(In Press Uncorrected Proof)
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08 December 2011 |
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Impact of Bone Marrow Hematogones on Umbilical Cord Blood Transplantation Outcomes in Patients with Acute Myeloid Leukemia
DOI: 10.1016/j.bbmt.2011.11.015
Early after umbilical cord blood transplantation, patients show marked differences in bone marrow (BM) hematogone percentages. Little is known about whether these differences are clinically relevant. ...
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Theodore Honebrink,
Vanessa Dayton,
Michael J. Burke,
Karen Larsen,
Qing Cao,
Claudio Brunstein,
Daniel Weisdorf,
Jeffery S. Miller,
John E. Wagner,
Michael R. Verneris
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Marrow versus Blood-Derived Stem Cell Grafts for Allogeneic Transplantation from Unrelated Donors in Patients with Active Myeloid Leukemia or Myelodysplasia
DOI: 10.1016/j.bbmt.2011.11.017
Peripheral blood stem cells (PBSCs) are increasingly used as the graft source in allogeneic hematopoietic cell transplantation. We compared long-term outcome after unrelated donor transplantation of 8...
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Hartmut Bertz,
Alexandros Spyridonidis,
Gabriele Ihorst,
Monika Engelhardt,
Carsten Grüllich,
Ralph Wäsch,
Reinhard Marks,
Jürgen Finke
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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The Triterpenoid CDDO-Me Promotes Hematopoietic Progenitor Expansion and Myelopoiesis in Mice
DOI: 10.1016/j.bbmt.2011.11.013
The synthetic triterpenoid CDDO-Me has been shown to directly inhibit the growth of myeloid leukemias and lends itself to a wide array of therapeutic indications, including inflammatory conditions, be...
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Erik Ames,
Salif Harouna,
Colin Meyer,
Lisbeth A. Welniak,
William J. Murphy
et al.
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Full-length article
(In Press Corrected Proof)
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18 November 2011 |
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Impact of a Conservative Red Blood Cell Transfusion Strategy in Children Undergoing Hematopoietic Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.043
A 2008 randomized trial of critically ill, but stable, children reported the safety of transfusing red blood cells at a hemoglobin threshold of 7 g/dL. In 2009, we adopted the same transfusion criteri...
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Jenifer R. Lightdale,
Adrienne G. Randolph,
Chau M. Tran,
Hongyu Jiang,
Andrea Colon,
Kathleen Houlahan,
Amy Billet,
Steven Sloan,
Leslie E. Lehmann
et al.
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Full-length article
(In Press Corrected Proof)
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14 November 2011 |
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Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Patients with Treatment-Related Myelodysplastic Syndrome or Acute Myelogenous Leukemia
DOI: 10.1016/j.bbmt.2011.11.009
The development of treatment-related myelodysplastic syndrome (tMDS) or treatment-related acute myelogenous leukemia (tAML) is a complication that can occur after chemotherapy or radiation therapy. Ei...
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Rachel Kobos,
Peter G. Steinherz,
Nancy A. Kernan,
Susan E. Prockop,
Andromachi Scaradavou,
Trudy N. Small,
Neerav Shukla,
Ramzi Khalaf,
Richard J. O’Reilly,
Farid Boulad
et al.
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Short communication
(In Press Corrected Proof)
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11 November 2011 |
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Phase I-II Study of Clofarabine-Melphalan-Alemtuzumab Conditioning for Allogeneic Hematopoietic Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.041
We conducted a phase I-II study of transplantation conditioning with clofarabine-melphalan-alemtuzumab for patients with advanced hematologic malignancies. Ten patients were accrued to the phase I por...
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Koen van Besien,
Wendy Stock,
Elizabeth Rich,
Olatoyosi Odenike,
Lucy A. Godley,
Peter H. O’Donnell,
Justin Kline,
Vu Nguyen,
Paula del Cerro,
Richard A. Larson,
Andrew S. Artz
et al.
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Full-length article
(In Press Corrected Proof)
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10 November 2011 |
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Significance of Increased Blastic-Appearing Cells in Bone Marrow Following Myeloablative Unrelated Cord Blood Transplantation in Adult Patients
DOI: 10.1016/j.bbmt.2011.11.008
An abnormal increase of nonleukemic blastic-appearing lymphocytes in bone marrow (BM) specimens has been reported after unrelated cord blood transplantation (UCBT). This study analyzed the incidence, ...
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Pau Montesinos,
Adriana Gascón,
David Martínez-Cuadrón,
María-Leonor Senent,
Lourdes Cordón,
Jaime Sanz,
Amparo Sempere,
María López-Pavía,
Rebeca Rodríguez-Veiga,
María J. Hurtado,
Federico Gomis,
Guillermo Martín,
Ignacio Lorenzo,
Javier Palau,
María D. Planelles,
Luis Larrea,
Nelly Carpio,
Mariluz Pérez-Sirvent,
Miguel A. Sanz,
Guillermo F. Sanz
et al.
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Full-length article
(In Press Corrected Proof)
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10 November 2011 |
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Evaluation of Oral Beclomethasone Dipropionate for Prevention of Acute Graft-versus-Host Disease
DOI: 10.1016/j.bbmt.2011.11.010
Results from two randomized trials have shown that oral beclomethasone dipropionate (BDP) is effective for treatment of acute gastrointestinal graft-versus-host disease. Here, we report results of a d...
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Paul J. Martin,
Terry Furlong,
Scott D. Rowley,
Steven A. Pergam,
Michele Lloid,
Mark M. Schubert,
Kevin J. Horgan,
Barry E. Storer
et al.
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Full-length article
(In Press Corrected Proof)
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10 November 2011 |
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In Situ Detection of HY-Specific T Cells in Acute Graft-versus-Host Disease–Affected Male Skin after Sex-Mismatched Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.038
HY-specific T cells are presumed to play a role in acute graft-versus-host disease (aGVHD) after female-to-male stem cell transplantation (SCT). However, infiltrates of these T cells in aGVHD-affected...
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Yeung-Hyen Kim,
Claudia M.J.M. Faaij,
Astrid G.S. van Halteren,
Ellen Schrama,
Trees A.M. de Jong,
Jørgen Schøller,
R. Maarten Egeler,
Stan Pavel,
Florry A. Vyth-Dreese,
Maarten J.D. van Tol,
Els Goulmy,
Eric Spierings
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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CD3+/Tregs Ratio in Donor Grafts Is Linked to Acute Graft-versus-Host Disease and Immunologic Recovery After Allogeneic Peripheral Blood Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.039
Graft-versus-host disease (GVHD), mediated by mature T cells present in the donor graft, remains a major complication after allogeneic peripheral blood stem cell transplantation (PBSCT). Regulatory T ...
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Domenico Pastore,
Mario Delia,
Anna Mestice,
Paola Carluccio,
Tommasina Perrone,
Francesco Gaudio,
Paola Curci,
Antonella Russo Rossi,
Alessandra Ricco,
Giorgina Specchia
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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Second Autologous Stem Cell Transplantation as Salvage Therapy for Multiple Myeloma: Impact on Progression-Free and Overall Survival
DOI: 10.1016/j.bbmt.2011.10.044
The role of a second autologous stem cell transplant (ASCT) as salvage therapy is unclear, particularly with the availability of novel agents to treat progressive multiple myeloma (MM). We retrospecti...
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Victor H. Jimenez-Zepeda,
Joseph Mikhael,
Andrew Winter,
Norman Franke,
Esther Masih-Khan,
Suzanne Trudel,
Christine Chen,
Vishal Kukreti,
Donna E. Reece
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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Relationship of Race/Ethnicity and Survival after Single Umbilical Cord Blood Transplantation for Adults and Children with Leukemia and Myelodysplastic Syndromes
DOI: 10.1016/j.bbmt.2011.10.040
The relationship of race/ethnicity with outcomes of umbilical cord blood transplantation (UCBT) is not well known. We analyzed the association between race/ethnicity and outcomes of unrelated single U...
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Karen K. Ballen,
John P. Klein,
Tanya L. Pedersen,
Deepika Bhatla,
Reggie Duerst,
Joanne Kurtzberg,
Hillard M. Lazarus,
Charles F. LeMaistre,
Phillip McCarthy,
Paulette Mehta,
Jeanne Palmer,
Michelle Setterholm,
John R. Wingard,
Steven Joffe,
Susan K. Parsons,
Galen E. Switzer,
Stephanie J. Lee,
J. Douglas Rizzo,
Navneet S. Majhail
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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Risk Factors for Progression from Cytomegalovirus Viremia to Cytomegalovirus Disease after Allogeneic Hematopoietic Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.037
Cytomegalovirus (CMV) disease is a major cause of infectious complications in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Although patients undergoing allo-HSCT receive prophylacti...
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Ji Eun Jang,
Shin Young Hyun,
Yun Deok Kim,
Sul Hee Yoon,
Doh Yu Hwang,
Soo Jeong Kim,
Yuri Kim,
Jin Seok Kim,
June-Won Cheong,
Yoo Hong Min
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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Outcomes of Allogeneic Hematopoietic Cell Transplantation for Adolescent and Young Adults Compared with Children and Older Adults with Acute Myeloid Leukemia
DOI: 10.1016/j.bbmt.2011.10.031
Adolescents and young adults (AYAs) with cancer have not experienced improvements in survival to the same extent as children and older adults. We compared outcomes among children (<15 years), AYAs ...
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Navneet S. Majhail,
Ruta Brazauskas,
Anna Hassebroek,
Christopher N. Bredeson,
Theresa Hahn,
Gregory A. Hale,
Mary M. Horowitz,
Hillard M. Lazarus,
Richard T. Maziarz,
William A. Wood,
Susan K. Parsons,
Steven Joffe,
J. Douglas Rizzo,
Stephanie J. Lee,
Brandon M. Hayes-Lattin
et al.
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Full-length article
(In Press Corrected Proof)
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31 October 2011 |
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Risk Factors for 30-Day Hospital Readmission following Myeloablative Allogeneic Hematopoietic Cell Transplantation (allo-HCT)
DOI: 10.1016/j.bbmt.2011.10.032
Patient readmission within 30 days from discharge has been perceived by the Centers for Medicare and Medical Services as an indicator of poor healthcare quality for specific high-cost medical conditio...
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Nelli Bejanyan,
Brian J. Bolwell,
Aleksandr Lazaryan,
Lisa Rybicki,
Shawnda Tench,
Hien Duong,
Steven Andresen,
Ronald Sobecks,
Robert Dean,
Brad Pohlman,
Matt Kalaycio,
Edward A. Copelan
et al.
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Full-length article
(In Press Corrected Proof)
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31 October 2011 |
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Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia-Positive Acute Lymphoblastic Leukemia in Children and Adolescents: A Retrospective Multicenter Study of the Italian Association of Pediatric Hematology and Oncology (AIEOP)
DOI: 10.1016/j.bbmt.2011.10.015
Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) still represents a major challenge. We report the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP) with a...
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Franca Fagioli,
Marco Zecca,
Carla Rognoni,
Edoardo Lanino,
Adriana Balduzzi,
Massimo Berger,
Chiara Messina,
Claudio Favre,
Marco Rabusin,
Luca Lo Nigro,
Riccardo Masetti,
Arcangelo Prete,
Franco Locatelli,
on behalf of the AIEOP-HSCT Group
et al.
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Full-length article
(In Press Corrected Proof)
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21 October 2011 |
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Pretransplantation Assessments and Symptom Profiles: Predicting Transplantation-Related Toxicity and Improving Patient-Centered Outcomes
DOI: 10.1016/j.bbmt.2011.10.014
With the advent of reduced-intensity conditioning regimens and improvements in supportive care, hematopoietic cell transplantation (HCT) has become increasingly available to older adults and medically...
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William A. Wood,
Amy P. Abernethy,
Sergio A. Giralt
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Full-length article
(In Press Corrected Proof)
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19 October 2011 |
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Reduced-Intensity Conditioning Stem Cell Transplantation: Comparison of Double Umbilical Cord Blood and Unrelated Donor Grafts
DOI: 10.1016/j.bbmt.2011.10.016
There are little data comparing umbilical cord blood (UBC) and conventional stem cell sources for reduced-intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT). We performed a re...
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Yi-Bin Chen,
Julie Aldridge,
Haesook T. Kim,
Karen K. Ballen,
Corey Cutler,
Grace Kao,
Deborah Liney,
Greg Bourdeau,
Edwin P. Alyea,
Philippe Armand,
John Koreth,
Jerome Ritz,
Thomas R. Spitzer,
Robert J. Soiffer,
Joseph H. Antin,
Vincent T. Ho
et al.
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Full-length article
(In Press Corrected Proof)
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19 October 2011 |
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Comparison of Unrelated Cord Blood Transplantation and HLA-Mismatched Unrelated Bone Marrow Transplantation for Adults with Leukemia
DOI: 10.1016/j.bbmt.2011.10.008
Recent advances in unrelated cord blood transplantation (UCBT) and high-resolution typing of human leukocyte antigen (HLA) from an unrelated donor have increased choices in alternative donor/stem cell...
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Yoshiko Atsuta,
Yasuo Morishima,
Ritsuro Suzuki,
Tokiko Nagamura-Inoue,
Shuichi Taniguchi,
Satoshi Takahashi,
Shunro Kai,
Hisashi Sakamaki,
Yasushi Kouzai,
Naoki Kobayashi,
Takahiro Fukuda,
Hiroshi Azuma,
Minoko Takanashi,
Takehiko Mori,
Masahiro Tsuchida,
Takakazu Kawase,
Keisei Kawa,
Yoshihisa Kodera,
Shunichi Kato,
for the Japan Marrow Donor Program and the Japan Cord Blood Bank Network
et al.
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Full-length article
(In Press Corrected Proof)
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17 October 2011 |
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High-Dose Therapy and Autologous Stem Cell Transplantation in First Relapse for Diffuse Large B Cell Lymphoma in the Rituximab Era: An Analysis Based on Data from the European Blood and Marrow Transplantation Registry
DOI: 10.1016/j.bbmt.2011.10.010
Autologous stem cell transplantation (ASCT) consolidation remains the treatment of choice for patients with relapsed diffuse large B cell lymphoma. The impact of rituximab combined with chemotherapy i...
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Nicolas Mounier,
Carmen Canals,
Christian Gisselbrecht,
Jan Cornelissen,
Roberto Foa,
Eulogio Conde,
John Maertens,
Michel Attal,
Alessandro Rambaldi,
Charles Crawley,
Jian-Jian Luan,
Mats Brune,
Sebastian Wittnebel,
Gordon Cook,
G.W. van Imhoff,
Michael Pfreundschuh,
Anna Sureda,
for the Lymphoma Working Party of the European Blood and Marrow Transplantation Registry (EBMT)
et al.
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Full-length article
(In Press Corrected Proof)
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17 October 2011 |
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Favorable Outcomes in Patients with High Donor-Derived T Cell Count after in Vivo T Cell–Depleted Reduced-Intensity Allogeneic Stem Cell Transplantation
DOI: 10.1016/j.bbmt.2011.10.011
Patients with hematologic malignancies were conditioned using a rabbit antithymocyte globulin–based reduced-intensity conditioning regimen for allogeneic stem cell transplantation. Donor-derived CD3+ ...
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Amir A. Toor,
Roy T. Sabo,
Harold M. Chung,
Catherine Roberts,
Rose H. Manjili,
Shiyu Song,
David C. Williams,
Wendy Edmiston,
Mandy L. Gatesman,
Richard W. Edwards,
Andrea Ferreira-Gonzalez,
William B. Clark,
Michael C. Neale,
John M. McCarty,
Masoud H. Manjili
et al.
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Full-length article
(In Press Corrected Proof)
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17 October 2011 |
